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===Complications=== Early complications include [[Shock (circulatory)|shock]], infection, [[systemic inflammatory response syndrome]], low blood calcium, high blood glucose, and [[dehydration]]. Blood loss, dehydration, and [[third spacing|fluid leaking]] into the [[abdominal cavity]] ([[ascites]]) can lead to [[kidney failure]]. Respiratory complications are often [[acute respiratory distress syndrome|severe]]. [[Pleural effusion]] is usually present. Shallow breathing from pain can lead to [[atelectasis|lung collapse]]. Pancreatic enzymes may attack the lungs, causing [[pneumonitis|inflammation]]. Severe inflammation can lead to intra-abdominal hypertension and [[abdominal compartment syndrome]], further impairing renal and respiratory function and potentially requiring management with an open abdomen to relieve the pressure.<ref>{{cite journal | vauthors = Fitzgerald JE, Gupta S, Masterson S, Sigurdsson HH | title = Laparostomy management using the ABThera™ open abdomen negative pressure therapy system in a grade IV open abdomen secondary to acute pancreatitis | journal = International Wound Journal | volume = 10 | issue = 2 | pages = 138–144 | date = April 2013 | pmid = 22487377 | pmc = 7950789 | doi = 10.1111/j.1742-481X.2012.00953.x | s2cid = 2459785 }}</ref> Late complications include recurrent pancreatitis and the development of [[pancreatic pseudocyst]]s—collections of pancreatic secretions that have been walled off by scar tissue. These may cause pain, become infected, rupture and bleed, block the bile duct and cause [[jaundice]], or migrate around the abdomen. Acute necrotizing pancreatitis can lead to a [[pancreatic abscess]], a collection of [[pus]] caused by [[necrosis]], [[liquefaction]], and [[infection]]. This happens in approximately 3% of cases or almost 60% of cases involving more than two pseudocysts and gas in the pancreas.<ref name="A">{{EMedicine|article|181264|Pancreatic abscess}}</ref>
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