Editing Oxycodone (section)

===Available forms===
{{See also|Oxycodone/paracetamol|Oxycodone/aspirin|Oxycodone/ibuprofen|Oxycodone/naloxone}}
{{Multiple image
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|image1=OxyContin branded oxycodone 10mg (OC side).jpg
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|footer=Both sides of a single 10mg OxyContin pill.
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Oxycodone is available in a variety of formulations for [[oral administration|by mouth]] or [[sublingual administration|under the tongue]]:<ref name="ElliottSmith2016" >{{cite book |vauthors=Elliott JA, Smith HS |title=Handbook of Acute Pain Management |url=https://books.google.com/books?id=Em7OBQAAQBAJ&pg=PA82 |date=19 April 2016 |publisher=CRC Press |isbn=978-1-4665-9635-1 |pages=82–}}</ref><ref name="PhD2006">{{cite book |vauthors=Gould III HJ |title=Understanding Pain: What It Is, Why It Happens, and How It's Managed |url=https://books.google.com/books?id=eKPudFvllpsC&pg=PA71|date=11 December 2006|publisher=Demos Medical Publishing|isbn=978-1-934559-82-6|pages=71–}}</ref><ref name="Graves2015">{{cite book|vauthors=Graves K |title=Drug I.D. & Symptom Guide |edition=6th |series=QWIK-CODE |url=https://books.google.com/books?id=yGyfCgAAQBAJ&pg=PT99 |date=29 September 2015|publisher=LawTech Publishing Group|isbn=978-1-56325-225-9 |pages=99–}}</ref><ref name="Skidmore-Roth2015">{{cite book |vauthors=Skidmore-Roth L |title=Mosby's Drug Guide for Nursing Students, with 2016 Update |url=https://books.google.com/books?id=g_BwCgAAQBAJ&pg=PA789 |date=16 July 2015 |publisher=Elsevier Health Sciences |isbn=978-0-323-17297-4 |pages=789– |access-date=5 October 2016 |archive-date=7 October 2022 |archive-url=https://web.archive.org/web/20221007000409/https://books.google.com/books?id=g_BwCgAAQBAJ&pg=PA789 |url-status=live}}</ref>

* Immediate-release oxycodone (OxyFast, OxyIR, OxyNorm, Roxicodone)
* Controlled-release oxycodone (OxyContin, Xtampza ER) – 10–12 hour duration<ref name="sunshine1996">{{cite journal |vauthors=Sunshine A, Olson NZ, Colon A, Rivera J, Kaiko RF, Fitzmartin RD, Reder RF, Goldenheim PD |date=July 1996 |title=Analgesic efficacy of controlled-release oxycodone in postoperative pain |journal=Journal of Clinical Pharmacology |volume=36 |issue=7 |pages=595–603 |doi=10.1002/j.1552-4604.1996.tb04223.x |pmid=8844441 |s2cid=35076787 |quote=Treatment with CR oxycodone was safe and effective in this study, and its characteristics will be beneficial in the treatment of pain.}}</ref>
* Oxycodone tamper-resistant (OxyContin OTR)<ref>{{cite web|url=http://www.accessdata.fda.gov/drugsatfda_docs/nda/2013/022272Orig1s014ClinPharmR.pdf|title=Clinical Pharmacology Review|publisher=U.S. [[Food and Drug Administration]] (FDA) |access-date=11 February 2018|archive-date=12 February 2017|archive-url=https://web.archive.org/web/20170212033248/http://www.accessdata.fda.gov/drugsatfda_docs/nda/2013/022272Orig1s014ClinPharmR.pdf|url-status=live}}</ref>
* Immediate-release oxycodone with [[paracetamol]] (acetaminophen) (Percocet, Endocet, Roxicet, Tylox)
* Immediate-release oxycodone with [[aspirin]] (Endodan, Oxycodan, Percodan, Roxiprin)
* Immediate-release oxycodone with [[ibuprofen]] (Combunox)<ref name="SinatraLeon-Cassasola2009">{{cite book|vauthors=Sinatra RS, de Leon-Cassasola OA|title=Acute Pain Management|url=https://books.google.com/books?id=ORpBaZnBSaQC&pg=PA198|date=27 April 2009|publisher=Cambridge University Press|isbn=978-0-521-87491-5|pages=198–|access-date=5 October 2016|archive-date=7 October 2022|archive-url=https://web.archive.org/web/20221007000410/https://books.google.com/books?id=ORpBaZnBSaQC&pg=PA198|url-status=live}}</ref>
* Controlled-release oxycodone with [[naloxone]] (Targin, Targiniq, Targinact)<ref name="StaatsSilverman2016">{{cite book|vauthors=Staats PS, Silverman SM|title=Controlled Substance Management in Chronic Pain: A Balanced Approach|url=https://books.google.com/books?id=-WxBDAAAQBAJ&pg=PA172|date=28 May 2016|publisher=Springer|isbn=978-3-319-30964-4|pages=172–|access-date=5 October 2016|archive-date=7 October 2022|archive-url=https://web.archive.org/web/20221007000410/https://books.google.com/books?id=-WxBDAAAQBAJ&pg=PA172|url-status=live}}</ref> – 10–12 hour duration<ref name="sunshine1996" />
* Controlled-release oxycodone with [[naltrexone]] (Troxyca) – 10–12 hour duration<ref name="sunshine1996"/><ref name="Pfizer2018">{{cite web |title=FDA Approves Troxyca® ER (Oxycodone Hydrochloride and Naltrexone Hydrochloride) Extended-release Capsules CII with Abuse-deterrent Properties for the Management of Pain |date=19 August 2016 |url=https://www.pfizer.com/news/press-release/press-release-detail/fda_approves_troxyca_er_oxycodone_hydrochloride_and_naltrexone_hydrochloride_extended_release_capsules_cii_with_abuse_deterrent_properties_for_the_management_of_pain |access-date=21 June 2018 |archive-date=25 September 2020 |archive-url=https://web.archive.org/web/20200925173435/https://www.pfizer.com/news/press-release/press-release-detail/fda_approves_troxyca_er_oxycodone_hydrochloride_and_naltrexone_hydrochloride_extended_release_capsules_cii_with_abuse_deterrent_properties_for_the_management_of_pain |url-status=live}}</ref>
[[File:Oxycodone Syrup 10mg per ml.jpg|thumb|A liquid solution containing 10mg of oxycodone per 1ml]]
In the US, oxycodone is only approved for use by mouth, available as tablets and oral solutions. [[Parenteral]] formulations of oxycodone (brand name OxyNorm) are also available in other parts of the world, however, and are widely used in the European Union.<ref name="Davis2009">{{cite book |vauthors=Davis MP |title=Opioids in Cancer Pain |url=https://books.google.com/books?id=aEzg6i2nPMQC&pg=PA158 |date=28 May 2009 |publisher=OUP Oxford |isbn=978-0-19-923664-0 |pages=155–158 |access-date=5 October 2016 |archive-date=7 October 2022 |archive-url=https://web.archive.org/web/20221007000410/https://books.google.com/books?id=aEzg6i2nPMQC&pg=PA158 |url-status=live}}</ref><ref name="Forbes2007">{{cite book |vauthors=Forbes K |title=Opioids in Cancer Pain |url=https://books.google.com/books?id=X7PjroLnaYQC&pg=PA64 |date=29 November 2007 |publisher=OUP Oxford |isbn=978-0-19-921880-6 |pages=64–65}}</ref><ref name="BradburyHodge2013">{{cite book |vauthors=Bradbury H, Hodge BS |title=Practical Prescribing for Medical Students |url=https://books.google.com/books?id=U5L3AgAAQBAJ&pg=PT93 |date=8 November 2013 |publisher=SAGE Publications |isbn=978-1-4462-9753-7 |pages=93– |access-date=5 October 2016 |archive-date=7 October 2022 |archive-url=https://web.archive.org/web/20221007000411/https://books.google.com/books?id=U5L3AgAAQBAJ&pg=PT93 |url-status=live}}</ref> In [[Spain]], the [[Netherlands]] and the [[United Kingdom]], oxycodone is approved for [[intravenous therapy|intravenous]] (IV) and [[intramuscular injection|intramuscular]] (IM) use. When first introduced in [[Germany]] during [[World War I]], both IV and IM administrations of oxycodone were commonly used for postoperative pain management of [[Central Powers]] soldiers.<ref name="Kalso2005">{{cite journal |vauthors=Kalso E |title=Oxycodone |journal=Journal of Pain and Symptom Management |volume=29 |issue=5 Suppl |pages=S47–S56 |date=May 2005 |pmid=15907646 |doi=10.1016/j.jpainsymman.2005.01.010 |doi-access=free}}</ref>