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=== Definition === The [[optic nerve]] comprises [[axon]]s that emerge from the [[retina]] of the [[Human eye|eye]] and carry visual information to the primary visual nuclei, most of which is relayed to the [[Occipital lobe|occipital cortex]] of the [[Human brain|brain]] to be processed into vision. The phrase optic neuritis is derived from the pathophysiologic changes observed in this disorder whereby the optic nerve (''optic'') becomes inflamed (''neuritis''). As such, optic neuritis is typically a manifestation of an underlying, causative etiology. Because of the breadth of underlying causes of optic neuritis, this disorder is typically classified into the subtypes of "typical" ON and "atypical" ON. Typical ON refers to a demyelinating etiology which most commonly stems from multiple sclerosis or standalone idiopathic disease.<ref name=":12">{{Cite journal |last1=Abel |first1=Anne |last2=McClelland |first2=Collin |last3=Lee |first3=Michael S. |date=2019-11-01 |title=Critical review: Typical and atypical optic neuritis |url=https://linkinghub.elsevier.com/retrieve/pii/S0039625719300414 |journal=Survey of Ophthalmology |volume=64 |issue=6 |pages=770β779 |doi=10.1016/j.survophthal.2019.06.001 |issn=0039-6257 |pmid=31229520}}</ref> Atypical ON essentially refers to optic neuritis from any other cause.<ref name=":12"/>
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