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=== Patterns of weakness === Various patterns of muscle weakness occur in different motor neuron diseases.<ref name=":7" /> Weakness can be symmetric or asymmetric, and it can occur in body parts that are distal, proximal, or both. According to Statland et al., there are three main weakness patterns that are seen in motor neuron diseases, which are:<ref name=":7" /><ref>{{cite journal | vauthors = Barohn RJ, Amato AA | title = Pattern-recognition approach to neuropathy and neuronopathy | journal = Neurologic Clinics | volume = 31 | issue = 2 | pages = 343β361 | date = May 2013 | pmid = 23642713 | pmc = 3922643 | doi = 10.1016/j.ncl.2013.02.001 }}</ref> # Asymmetric distal weakness without sensory loss (e.g. ALS, PLS, PMA, MMA) # Symmetric weakness without sensory loss (e.g. PMA, PLS) # Symmetric focal midline proximal weakness (neck, trunk, bulbar involvement; e.g. ALS, PBP, PLS)
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