Editing Mifepristone (section)

===Abortion===
Mifepristone followed by a [[prostaglandin]] [[prostaglandin analogue|analog]] ([[misoprostol]] or [[gemeprost]]) is used for [[medical abortion]].<ref name="Mifegyne SPC 2015">{{cite web |author= |date=21 November 2022 |title=Mifegyne 200 Mg Tablets Summary of Product Characteristics (SPC) |url=https://mhraproducts4853.blob.core.windows.net/docs/da0a3830e2ed46fc9835502a30ab00a2be19f8fc |access-date=22 April 2023 |publisher=[[Medicines and Healthcare products Regulatory Agency]] (MHRA) |archive-date=23 April 2023 |archive-url=https://web.archive.org/web/20230423003527/https://mhraproducts4853.blob.core.windows.net/docs/da0a3830e2ed46fc9835502a30ab00a2be19f8fc |url-status=live }}</ref><ref name="FDA Mifeprex Info 2016">{{cite web |author= |date=23 March 2023 |title=Information about Mifepristone for Medical Termination of Pregnancy Through Ten Weeks Gestation |url=https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/information-about-mifepristone-medical-termination-pregnancy-through-ten-weeks-gestation |url-status=live |archive-url=https://web.archive.org/web/20230421235002/https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/information-about-mifepristone-medical-termination-pregnancy-through-ten-weeks-gestation |archive-date=21 April 2023 |access-date=22 April 2023 |website=Drugs |publisher=U.S. [[Food and Drug Administration]] (FDA) }}</ref> Medical organizations have found this combination to be safe and effective. Guidelines from the [[Royal College of Obstetricians and Gynaecologists]] describe medication abortion using mifepristone and [[misoprostol]] as effective and appropriate at any [[gestational age]].<ref name="RCOG 2011">{{cite book |url=https://www.rcog.org.uk/media/nwcjrf0o/abortion-guideline_web_1.pdf |title=The Care of Women Requesting Induced Abortion |date=November 2011 |publisher=[[RCOG]] Press |edition=3rd |series=Evidence-based Clinical Guideline No. 7 |location=London |pages=68–75 |access-date=25 April 2023 |archive-url=https://web.archive.org/web/20220526233950/https://www.rcog.org.uk/media/nwcjrf0o/abortion-guideline_web_1.pdf |archive-date=26 May 2022 |url-status=live}}</ref> The [[World Health Organization]] and the [[American College of Obstetricians and Gynecologists]] recommend mifepristone followed by misoprostol for first- and second-[[Trimester (pregnancy)|trimester]] medical abortion.<ref name="WHO 2012">{{cite book |author=World Health Organization |url=https://apps.who.int/iris/bitstream/handle/10665/70914/9789241548434_eng.pdf |title=Safe abortion: technical and policy guidance for health systems |date=21 June 2012 |publisher=WHO |isbn=978-92-4-154843-4 |edition=2nd |location=Geneva |pages=113–116 |language=en |chapter=Annex 5 |hdl=10665/70914 |hdl-access=free |access-date=26 April 2023 |archive-date=10 February 2023 |archive-url=https://web.archive.org/web/20230210092721/http://apps.who.int/iris/bitstream/handle/10665/70914/9789241548434_eng.pdf |url-status=live }}</ref><ref name="WHO 2014">{{cite book |url=http://apps.who.int/iris/bitstream/handle/10665/97415/9789241548717_eng.pdf |title=Clinical practice handbook for safe abortion |date=10 January 2014 |publisher=[[World Health Organization]] |isbn=978-92-4-154871-7 |location=Geneva |language=en |hdl=10665/97415 |hdl-access=free |access-date=26 April 2023 |archive-date=8 April 2023 |archive-url=https://web.archive.org/web/20230408070843/https://apps.who.int/iris/bitstream/handle/10665/97415/9789241548717_eng.pdf |url-status=live }}</ref><ref>{{Cite web |last=Committee on Practice Bulletins—Gynecology and the Society of Family Planning |date=October 2020 |title=Medication Abortion Up to 70 Days of Gestation |url=https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2020/10/medication-abortion-up-to-70-days-of-gestation |access-date=25 April 2023 |series=Practice Bulletin 225 |publisher=[[American College of Obstetricians and Gynecologists]] |archive-date=25 April 2023 |archive-url=https://web.archive.org/web/20230425173524/https://www.acog.org/clinical/clinical-guidance/practice-bulletin/articles/2020/10/medication-abortion-up-to-70-days-of-gestation |url-status=live }}</ref><ref name="ACOG 2013">{{cite journal |last=Committee on Practice Bulletins—Gynecology |date=June 2013 |title=Practice Bulletin No. 135: Second-Trimester Abortion |url=https://blog.utp.edu.co/maternoinfantil/files/2012/04/135-Aborto-2-trimestre.pdf |journal=[[Obstetrics & Gynecology (journal)|Obstetrics & Gynecology]] |volume=121 |issue=6 |pages=1394–1406 |doi=10.1097/01.AOG.0000431056.79334.cc |pmid=23812485 |s2cid=205384119 |via=[[Universidad Tecnológica de Pereira]] |access-date=26 April 2023 |archive-date=6 April 2023 |archive-url=https://web.archive.org/web/20230406064221/https://blog.utp.edu.co/maternoinfantil/files/2012/04/135-Aborto-2-trimestre.pdf |url-status=live }}</ref> Mifepristone alone is less effective, resulting in abortion within 1–2 weeks in anywhere from 54% to 92% of pregnancies, according to review of 13 studies.<ref name=Gross2015/>