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===Paracelsus's laudanum=== [[Paracelsus]], a 16th-century [[German-speaking Swiss|Swiss]] [[alchemist]], experimented with various [[opium]] concoctions, and recommended opium for reducing pain. One of his preparations, a pill which he extolled as his "archanum" or "laudanum", may have contained opium.<ref name="Sigerist">{{cite journal | vauthors = Sigerist HE |title=Laudanum in the Works of Paracelsus |journal=Bull. Hist. Med. |date=1941 |volume=9 |pages=530β544 |url=http://www.samorini.it/doc1/alt_aut/sz/sigerist-laudanum-in-the-work-of-paracelsus.pdf |archive-url=https://ghostarchive.org/archive/20221009/http://www.samorini.it/doc1/alt_aut/sz/sigerist-laudanum-in-the-work-of-paracelsus.pdf |archive-date=2022-10-09 |url-status=live |access-date=5 September 2018}}</ref> Paracelsus's laudanum was strikingly different from the standard laudanum of the 17th century and beyond, containing crushed [[pearls]], [[musk]], [[amber]], and other substances.<ref name=Davenport-Hines>{{cite book | vauthors = Davenport-Hines R | author-link1 = Richard Davenport-Hines | title = The Pursuit of Oblivion | year = 2004 | url = https://books.google.com/books?id=dFRd2MMrtiUC&q=laudanum+history+paracelsus&pg=PA31 | access-date = 2009-01-16 | chapter = Early History | publisher = Norton | chapter-url = https://books.google.com/books?id=dFRd2MMrtiUC&q=laudanum+history+paracelsus&pg=PA31 | ref = Davenport-Hines | isbn = 9780393325454 }}</ref>
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