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=== Biosynthesis === In plants and microorganisms, isoleucine is synthesized from [[Pyruvic acid|pyruvate]] and [[Alpha-Ketobutyric acid|alpha-ketobutyrate]]. This pathway is not present in humans. Enzymes involved in this biosynthesis include:<ref name="Lehninger_2000">{{Cite book | vauthors = Lehninger AL, Nelson DL, Cox MM |url=https://www.worldcat.org/oclc/42619569 |title=Lehninger principles of biochemistry. |date=2000 |publisher=Worth Publishers |isbn=1-57259-153-6 |edition=3rd |location=New York |oclc=42619569}}</ref> # [[Acetolactate synthase]] (also known as acetohydroxy acid synthase) # [[Acetohydroxy acid isomeroreductase]] # [[Dihydroxyacid dehydratase]] # [[Valine-3-methyl-2-oxovalerate transaminase|Valine aminotransferase]]
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