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Ipomoea corymbosa
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==Chemical properties== [[File:Oliluiqui Seeds.jpg|thumb|Seeds of ''Ipomoea corymbosa'' (Synonyms: ''Rivea corymbosa'' and ''Turbina corymbosa'')]] {{More citations needed|section|date=April 2016}} The [[Nahuatl]] word ''ololiuhqui'' means "round thing", and refers to the small, brown, oval seeds of the morning glory,<ref name="Carod">{{cite journal|last=Carod-Artal|first=FJ|title=Hallucinogenic drugs in pre-Columbian Mesoamerican cultures|journal=Neurologia|year=2015|volume=30|issue=1|pages=42–9|pmid=21893367|doi=10.1016/j.nrl.2011.07.003|url=http://www.elsevier.es/en-revista-neurologia-english-edition--495-pdf-S2173580814001527-S300|doi-access=free}}</ref> not the plant itself, which is called ''coaxihuitl'' (“snake-plant") in Nahuatl, and ''hiedra'', ''bejuco'' or ''quiebraplatos'' in the [[Spanish language]]. The seeds, in Spanish, are sometimes called ''semilla de la Virgen'' (seeds of the [[Blessed Virgin Mary|Virgin Mary]]).{{Citation needed|reason=disputed fact|date=June 2012}} While little of it is known outside of [[Mexico]], its seeds were perhaps the most common [[psychedelic drug]] used by the natives.<ref>{{Cite book |last=Ruck |first=Carl A. P. |title=Sacred Mushrooms of the Goddess: The Secrets of Eleusis |date=2006 |publisher=Ronin Publishing, Inc |isbn=978-1-57951-030-5 |location=Berkeley, California | postscript=<br>“Ololiuhqui was far more prominent as an entheogen here in Mesoamerica than those mushrooms; the mushrooms are mentioned only here and there by a few competent chroniclers; yet almost an entire book was devoted to denouncing mainly the ololiuhqui idolatry. The annals of the Inquisition contain many times more autos de fe for ololiuhqui than for mushrooms.” Jonathan Ott, 15. Mixing the Kykeon Anew (section: Ergine)}}</ref> In 1941, [[Richard Evans Schultes]] first identified ololiuhqui as ''Turbina corymbosa'' and the chemical composition was first described in 1960 in a paper by [[Albert Hofmann]].<ref>{{cite journal|last1=Hofmann|first1=A|last2=Tscherter|first2=H|title=Isolation of lysergic acid alkaloids from the Mexican drug ololiuqui (Rivea corymbosa (L.) Hall.f.)|journal=Experientia|date=15 September 1960|volume=16|page=414|pmid=13715089|doi=10.1007/bf02178840|s2cid=40460179|doi-access=free}}</ref> The seeds contain [[ergine]] (LSA), an [[ergoline]] [[alkaloid]] which is also present in [[claviceps purpurea|ergot of rye]] and is similar in structure to [[LSD]]. Ergot of rye was part of the [[Kykeon]], the drink which was a component of the [[Eleusinian mysteries]].<ref name="Rätsch">{{cite book|first=Ch|last=Rätsch|title=Enzyklopädie der psychoaktiven Pflanzen|edition=3rd|publisher=AT Verlag|location=Aarau|year=1998|isbn=3-85502-570-3}}</ref> The psychedelic properties of ''Turbina corymbosa'' and a comparison of the potency of different varieties were studied in the [[Central Intelligence Agency]]'s [[MKULTRA]] Subproject 22 in 1956. {{quote|My chemical investigations of ''Ololiuhqui'' seeds led to the unexpected discovery that the entheogenic principles of ''Ololiuhqui'' are alkaloids, especially lysergic acid amide, which exhibits a very close relationship to lysergic acid diethylamide (<nowiki>=</nowiki>ʟsᴅ). It follows therefrom that ʟsᴅ, which hitherto had been considered to be a synthetic product of the laboratory, actually belongs to the group of sacred Mexican drugs.|author=Albert Hofmann, Burg i.L., Switzerland, November 1992<ref>{{Cite book |last=Ott |first=Jonathan |title=Pharmacotheon: Entheogenic Drugs, Their Plant Sources and History |publisher=Natural Products Co. |isbn=9780961423490 |edition=2nd Edition, Densified |publication-date=1996 |pages=13 |chapter=Foreword |orig-date=1993-07}}</ref>}}
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