Editing Intracytoplasmic sperm injection (section)

==Indications==
[[File:Blausen 0060 AssistedReproductiveTechnology.png|thumb|Schematic image of intracytoplasmic sperm injection in the context of [[in vitro fertilisation|IVF]].]]

This procedure is most commonly used to overcome male [[infertility]] problems, although it may also be used where eggs cannot easily be penetrated by sperm, and occasionally in addition to [[sperm donation]].<ref>{{cite journal | vauthors = Boulet SL, Mehta A, Kissin DM, Warner L, Kawwass JF, Jamieson DJ | title = Trends in use of and reproductive outcomes associated with intracytoplasmic sperm injection | journal = JAMA | volume = 313 | issue = 3 | pages = 255–263 | date = January 2015 | pmid = 25602996 | pmc = 4343214 | doi = 10.1001/jama.2014.17985 }}</ref>

It can be used in [[teratozoospermia]], because once the egg is fertilized, abnormal sperm morphology does not appear to influence [[blastocyst]] development or blastocyst morphology.<ref name="French et al 2010">{{cite journal | vauthors = French DB, Sabanegh ES, Goldfarb J, Desai N | title = Does severe teratozoospermia affect blastocyst formation, live birth rate, and other clinical outcome parameters in ICSI cycles? | journal = Fertility and Sterility | volume = 93 | issue = 4 | pages = 1097–1103 | date = March 2010 | pmid = 19200957 | doi = 10.1016/j.fertnstert.2008.10.051 | doi-access = free }}</ref> Even with severe teratozoospermia, microscopy can still detect the few sperm cells that have a "normal" morphology, allowing for optimal success rate.<ref name="French et al 2010" />

Additionally, specialists use ICSI in cases of [[azoospermia]] (when there are no spermatozoa ejaculated but they can be found in [[testis]]), when valious spermatozoa (the name given to sperm samples taken to preservate fertility after [[chemotherapy]]) is available, or after previous irruptions in [[in vitro fertilisation|IVF]] cycles.