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==Non-deliberate immunosuppression== [[File:Acute leukemia-ALL.jpg|thumb|260 px|Leukemia]] {{Further|Immunodeficiency}} Non-deliberate immunosuppression can occur in, for example, [[ataxia–telangiectasia]], [[complement deficiency|complement deficiencies]], many types of [[cancer]], and certain chronic infections such as [[HIV/AIDS|human immunodeficiency virus]] (HIV). The unwanted effect in non-deliberate immunosuppression is [[immunodeficiency]] that results in increased susceptibility to [[pathogen]]s, such as bacteria and viruses.<ref name=2nih/> Immunodeficiency is also a potential adverse effect of many [[immunosuppressant drug]]s, in this sense, the scope of the term ''immunosuppression'' in general includes both beneficial and potential adverse effects of decreasing the function of the immune system.<ref>{{Cite journal|last1=Lallana|first1=Enrico C|last2=Fadul|first2=Camilo E|date=2011|title=Toxicities of Immunosuppressive Treatment of Autoimmune Neurologic Diseases|journal=Current Neuropharmacology|volume=9|issue=3|pages=468–477|doi=10.2174/157015911796557939|issn=1570-159X|pmc=3151601|pmid=22379461}}</ref> [[B cell]] deficiency and [[T cell]] deficiency are immune impairment that individuals are born with or are acquired, which in turn can lead to immunodeficiency problems.<ref>{{Cite web|url=https://patient.info/doctor/immunodeficiency-primary-and-secondary|title=Immunodeficiency (Primary and Secondary). Information.|website=patient.info|language=en-GB|access-date=2017-07-13}}</ref> [[Nezelof syndrome]] is an example of an immunodeficiency of T-cells.<ref>{{cite book|last1=Disorders|first1=National Organization for Rare|title=NORD Guide to Rare Disorders|date=2003|publisher=Lippincott Williams & Wilkins|isbn=9780781730631|page=408|url=https://books.google.com/books?id=99YPDvFWBB0C&q=Nezelof+syndrome&pg=PA408|access-date=2 June 2017|language=en}}</ref>
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