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===Myxedema coma=== {{Multiple image <!-- Essential parameters --> | align = right | direction = horizontal | width = 175 <!-- Image 1 --> | image1 = Myxedema face.png | caption1 = Man with myxedema or severe hypothyroidism showing an expressionless face, puffiness around the eyes, and pallor <!-- Image 2 --> | image2 = Myxedema standing.png | caption2 = Additional symptoms include swelling of the arms and legs and [[ascites]].}} [[Myxedema coma]] is a rare but life-threatening state of extreme hypothyroidism.<!-- <ref name=Klubo/> --> It may occur in those with established hypothyroidism when they develop an acute illness. Myxedema coma can be the first presentation of hypothyroidism.<!-- <ref name=Klubo/> --> People with myxedema coma typically have a [[hypothermia|low body temperature]] without shivering, [[altered level of consciousness|confusion]], a [[Bradycardia|slow heart rate]] and [[Hypoventilation|reduced breathing effort]].<!-- <ref name=Klubo/> --> There may be physical signs suggestive of hypothyroidism, such as skin changes or [[Macroglossia|enlargement of the tongue]].<ref name=Klubo>{{cite journal | vauthors = Klubo-Gwiezdzinska J, Wartofsky L | title = Thyroid emergencies | journal = The Medical Clinics of North America | volume = 96 | issue = 2 | pages = 385β403 | date = March 2012 | pmid = 22443982 | doi = 10.1016/j.mcna.2012.01.015 }}</ref>
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