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===Recreational=== [[Bayer]]'s original trade name of heroin is typically used in non-medical settings. It is used as a recreational drug for the [[Euphoria (emotion)|euphoria]] it induces. [[Anthropology|Anthropologist]] Michael Agar once described heroin as "the perfect whatever drug."<ref name="agar">{{cite web | vauthors = Agar M | title = Dope Double Agent: The Naked Emperor on Drugs | url = http://www.americanethnography.com/article_sql.php?id=95 | access-date = 22 October 2009 | quote = What a great New York drug heroin was, I thought. As any city, but more than most, New York is an information overload, a constant perceptual tornado that surrounds you most places you walk on the streets. Heroin is the audio-visual technology that helps manage that overload by dampening it in general and allowing a focus on some part of it that the human perceptual equipment was, in fact, designed to handle. | url-status = live | archive-url = https://web.archive.org/web/20091117152041/http://www.americanethnography.com/article_sql.php?id=95 | archive-date = 17 November 2009}}</ref> [[Physiological tolerance|Tolerance]] develops quickly, and increased doses are needed in order to achieve the same effects. Its popularity with recreational drug users, compared to [[morphine]], reportedly stems from its perceived different effects.<ref>{{cite journal|author1-link=Wolfgang Tschacher | vauthors = Tschacher W, Haemmig R, Jacobshagen N | title = Time series modeling of heroin and morphine drug action | journal = Psychopharmacology | volume = 165 | issue = 2 | pages = 188β93 | date = January 2003 | pmid = 12404073 | doi = 10.1007/s00213-002-1271-3 | s2cid = 33612363 | url = https://boris.unibe.ch/21515/ }}</ref> Short-term addiction studies by the same researchers demonstrated that tolerance developed at a similar rate to both heroin and morphine. When compared to the opioids [[hydromorphone]], [[fentanyl]], [[oxycodone]], and [[pethidine]] (meperidine), former addicts showed a strong preference for heroin and morphine, suggesting that heroin and morphine are particularly susceptible to misuse and causing dependence. Morphine and heroin were also much more likely to produce euphoria and other positive subjective effects when compared to these other opioids.<ref name="martin and fraser">{{cite journal | vauthors = Martin WR, Fraser HF | title = A comparative study of physiological and subjective effects of heroin and morphine administered intravenously in postaddicts | journal = The Journal of Pharmacology and Experimental Therapeutics | volume = 133 | pages = 388β99 | date = September 1961 | issue = 3 | doi = 10.1016/S0022-3565(25)26119-5 | pmid = 13767429 | url = http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=13767429 }}</ref>
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