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Fragile X syndrome
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===Physical phenotype=== * Large, [[protruding ears]] (both) * Long face ([[vertical maxillary excess]]) * [[High-arched palate]] (related to the above) * [[Hypermobility (joints)|Hyperextensible finger joints]] * Hyperextensible thumbs ('double-jointed') * [[Flat feet]] * Soft skin{{vague|date=November 2020}} * Postpubescent [[macroorchidism]] (large testicles in males after puberty)<ref>{{cite book| vauthors = Jordan JA, Regezi JJ, Sciubba RC |title=Oral pathology : clinical pathologic correlations|year=2008|publisher=Saunders/Elsevier|location=St. Louis, Mo.|isbn=978-1-4160-4570-0|edition=5th|chapter=15}} Section on fragile X syndrome{{page needed|date=December 2013}}</ref> * [[Hypotonia]] (low muscle tone)<ref>{{cite journal | vauthors = Nichols C, Nichols D |title=Fragile X Syndrome: Implications for Physical Education |journal=Palaestra |date=1 June 2019 |volume=33 |issue=3}}</ref><ref name=book2>{{cite book | vauthors = Goldstein S, Reynolds CR |title=Handbook of neurodevelopmental and genetic disorders in children |location=New York |publisher=Guilford Press |year=1999 |isbn=978-1-57230-448-2}}{{page needed|date=December 2013}}</ref>
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