Editing Coal tar (section)

===Derivatives===
Various [[phenols|phenolic]] coal tar derivatives have [[analgesic]] (pain-killer) properties. These included [[acetanilide]], [[phenacetin]], and [[paracetamol]] aka [[acetaminophen]].<ref name="para">{{cite magazine | vauthors = Dronsfield A |date=1 July 2005 |title=Pain relief: from coal tar to paracetamol |url=https://eic.rsc.org/feature/pain-relief-from-coal-tar-to-paracetamol/2020140.article |volume=42 |issue=4 |pages=102–105 |url-status=live |magazine=[[Education in Chemistry]] |publisher=[[Royal Society of Chemistry]] |archive-url=https://web.archive.org/web/20171013013607/https://eic.rsc.org/feature/pain-relief-from-coal-tar-to-paracetamol/2020140.article |archive-date=13 October 2017 |access-date=14 June 2018}}</ref> Paracetamol may be the only coal-tar derived analgesic still in use today.<ref name="rscbde05">{{cite news | vauthors = Brown T, Dronsfield A, Ellis P |title=Pain relief: from coal tar to paracetamol |url=https://edu.rsc.org/feature/pain-relief-from-coal-tar-to-paracetamol/2020140.article |publisher=Royal Society of Chemistry |date=1 July 2005}}</ref> Industrial [[phenol]] is now usually synthesized from crude oil rather than coal tar.<ref name="jones11">{{cite journal | vauthors = Jones AW | title = Early drug discovery and the rise of pharmaceutical chemistry | journal = Drug Testing and Analysis | volume = 3 | issue = 6 | pages = 337–44 | date = June 2011 | pmid = 21698778 | doi = 10.1002/dta.301 }}</ref>

Coal tar derivatives are contra-indicated for people with the inherited red cell blood disorder [[glucose-6-phosphate dehydrogenase deficiency]] (G6PD deficiency), as they can cause oxidative stress leading to red blood cell breakdown.<ref name=epahema>{{cite web | author = US EPA National Center for Environmental Assessment |title=Hematologic Disorders |url=https://hero.epa.gov/hero/index.cfm/reference/details/reference_id/1390864 |website=hero.epa.gov |access-date=21 April 2020 |language=en |date=15 March 2009}}</ref>