Editing Clinical death (section)

==Hypothermia==
Reduced body temperature, or [[therapeutic hypothermia]], during clinical death slows the rate of injury accumulation, and extends the time period during which clinical death can be survived.  The decrease in the rate of injury can be approximated by the [[Q10 (temperature coefficient)|Q<sub>10</sub>]] rule, which states that the rate of biochemical reactions decreases by a factor of two for every 10&nbsp;°C reduction in temperature. As a result, humans can sometimes survive periods of clinical death exceeding one hour at temperatures below 20&nbsp;°C.<ref>{{cite journal
| last1 = Walpoth BH
| title = Accidental deep hypothermia with cardiopulmonary arrest: extracorporeal blood rewarming in 11 patients
| journal = European Journal of Cardio-Thoracic Surgery
| volume = 4
| pages = 390–93
| year = 1990
| publisher = Elsevier Science
| pmid=2397132
| doi = 10.1016/1010-7940(90)90048-5
| first1 = BH
| last2 = Locher
| first2 = T
| last3 = Leupi
| first3 = F
| last4 = Schüpbach
| first4 = P
| last5 = Mühlemann
| first5 = W
| last6 = Althaus
| first6 = U
| issue = 7|display-authors=etal}}</ref>  The prognosis is improved if clinical death is caused by hypothermia rather than occurring prior to it; in 1999, 29-year-old Swedish woman [[Anna Bågenholm]] spent 80 minutes trapped in ice and survived with a near full recovery from a 13.7&nbsp;°C core body temperature. It is said in emergency medicine that "nobody is dead until they are warm and dead."<ref>{{cite news
| title = Skier revived from clinical death
| work = BBC News
| date = 18 January 2000
| url = http://news.bbc.co.uk/2/hi/health/620609.stm
| access-date = 9 January 2007}}</ref>  In animal studies, up to three hours of clinical death can be survived at temperatures near 0&nbsp;°C.<ref>{{cite journal
| last1 = Haneda K
| title = Whole body protection during three hours of total circulatory arrest: an experimental study
| journal = Cryobiology
| volume = 23
| pages = 483–94
| year = 1986
| publisher = Academic Press
| pmid=3802887
| doi = 10.1016/0011-2240(86)90057-X
| first1 = K
| last2 = Thomas
| first2 = R
| last3 = Sands
| first3 = MP
| last4 = Breazeale
| first4 = DG
| last5 = Dillard
| first5 = DH
| issue = 6|display-authors=etal}}</ref><ref>{{cite journal
| last1 = Behringer W, Safar P
| title = Survival without brain damage after clinical death of 60–120 mins in dogs using suspended animation by profound hypothermia
| journal = Critical Care Medicine
| volume = 31
| pages = 1592–93
| year = 2003
| publisher = Lippincott Williams & Wilkins
| pmid=12771628
| doi = 10.1097/01.CCM.0000063450.73967.40
| first1 = W
| last2 = Safar
| first2 = P
| last3 = Wu
| first3 = X
| last4 = Kentner
| first4 = R
| last5 = Radovsky
| first5 = A
| last6 = Kochanek
| first6 = PM
| last7 = Dixon
| first7 = CE
| last8 = Tisherman
| first8 = SA
| issue = 5| s2cid = 12947736
|display-authors=etal}}</ref>