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===Pregnancy=== An expert review of published data on experiences with ciprofloxacin use during pregnancy concluded therapeutic doses during pregnancy are unlikely to pose a substantial teratogenic risk (quantity and quality of data=fair), but the data is insufficient to state that no risks exist.<ref>{{cite journal |vauthors = Barolin GS |title = [Illness, anxiety and the physician. An example from neurology and neurorehabilitation] |journal = Wiener Medizinische Wochenschrift |volume = 141 |issue = 22 |pages = 512β25 |date = May 1995 |pmid = 1801454 |pmc = 1801454 }}</ref> Exposure to quinolones, including levofloxacin, during the first-trimester is not associated with an increased risk of stillbirths, premature births, birth defects, or low birth weight.<ref>{{cite journal |vauthors=Ziv A, Masarwa R, Perlman A, Ziv D, Matok I |title=Pregnancy Outcomes Following Exposure to Quinolone Antibiotics β a Systematic-Review and Meta-Analysis |journal=Pharm. Res. |volume=35 |issue=5 |pages=109 |date=March 2018 |pmid=29582196 |doi=10.1007/s11095-018-2383-8 |s2cid=4724821 }}</ref> Two small post-marketing epidemiology studies of mostly short-term, first-trimester exposure found that fluoroquinolones did not increase risk of major malformations, spontaneous abortions, premature birth, or low birth weight.<ref name="pmid9624471">{{cite journal |vauthors = Loebstein R, Addis A, Ho E, Andreou R, Sage S, Donnenfeld AE, Schick B, Bonati M, Moretti M, Lalkin A, Pastuszak A, Koren G |title = Pregnancy outcome following gestational exposure to fluoroquinolones: a multicenter prospective controlled study |journal = Antimicrobial Agents and Chemotherapy |volume = 42 |issue = 6 |pages = 1336β9 |date = June 1998 |pmid = 9624471 |pmc = 105599 |doi = 10.1128/AAC.42.6.1336 }}</ref><ref name="pmid8902438">{{cite journal |vauthors = Schaefer C, Amoura-Elefant E, Vial T, Ornoy A, Garbis H, Robert E, Rodriguez-Pinilla E, Pexieder T, Prapas N, Merlob P |title = Pregnancy outcome after prenatal quinolone exposure. Evaluation of a case registry of the European Network of Teratology Information Services (ENTIS) |journal = European Journal of Obstetrics, Gynecology, and Reproductive Biology |volume = 69 |issue = 2 |pages = 83β9 |date = November 1996 |pmid = 8902438 |doi = 10.1016/0301-2115(95)02524-3}}</ref>
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