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==Reactions of chloride== Chloride can be oxidized but not reduced. The first oxidation, as employed in the chlor-alkali process, is conversion to chlorine gas. Chlorine can be further oxidized to other oxides and oxyanions including [[hypochlorite]] (ClO<sup>β</sup>, the active ingredient in chlorine [[bleach]]), [[chlorine dioxide]] (ClO<sub>2</sub>), [[chlorate]] ({{chem|ClO|3|β}}), and [[perchlorate]] ({{chem|ClO|4|β}}). In terms of its acidβbase properties, chloride is a [[weak base]] as indicated by the negative value of the [[pKa|p''K''<sub>a</sub>]] of hydrochloric acid. Chloride can be protonated by [[strong acid]]s, such as sulfuric acid: :NaCl + H<sub>2</sub>SO<sub>4</sub> β NaHSO<sub>4</sub> + HCl Ionic chloride salts react with other salts to exchange anions. The presence of halide ions like chloride can be detected using [[silver nitrate]]. A solution containing chloride ions will produce a white [[silver chloride]] precipitate:<ref>{{Cite web |title=Testing for halide ions - Group 0 and testing ions - GCSE Chemistry (Single Science) Revision - WJEC |url=https://www.bbc.co.uk/bitesize/guides/zm426yc/revision/2 |access-date=2022-03-03 |website=BBC Bitesize |language=en-GB}}</ref> :Cl<sup>β</sup> + Ag<sup>+</sup> β AgCl The concentration of chloride in an assay can be determined using a [[chloridometer]], which detects silver ions once all chloride in the assay has precipitated via this reaction. [[Silver chloride electrode|Chlorided silver electrodes]] are commonly used in {{Lang|la|ex vivo}} [[electrophysiology]].<ref>Molleman, Areles (2003). "Patch Clamping: An Introductory Guide to Patch Clamp Electrophysiology". Wiley & Sons. {{ISBN|978-0-471-48685-5}}.</ref>
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