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==Causes== Apraxia is most often due to a lesion located in the dominant (usually left) hemisphere of the brain, typically in the [[frontal lobe|frontal]] and [[parietal lobe]]s. Lesions may be due to [[stroke]], [[acquired brain injury|acquired brain injuries]], or [[Neurodegeneration|neurodegenerative diseases]] such as [[Alzheimer's disease]] or other [[dementia]]s, [[Parkinson's disease]], or [[Huntington's disease]]. Also, apraxia possibly may be caused by lesions in other areas of the brain.<ref name=Gross /> Ideomotor apraxia is typically due to a decrease in blood flow to the dominant hemisphere of the brain and particularly the [[parietal area|parietal]] and [[premotor area|premotor]] areas. It is frequently seen in patients with [[corticobasal degeneration]].<ref name=Gross /> Ideational apraxia has been observed in patients with lesions in the dominant hemisphere near areas associated with [[aphasia]], but more research is needed on ideational apraxia due to brain lesions. The localization of lesions in areas of the frontal and temporal lobes would provide explanation for the difficulty in motor planning seen in ideational apraxia, as well as its difficulty to distinguish it from certain aphasias.<ref name= Tonkonogy>{{cite book |last1=Tonkonogy |first1=Joseph |last2=Puente |first2=Antonio |title=Localization of clinical syndromes in neuropsychology and neuroscience |publisher=Springer Publishing Company |year=2009 |pages=291β323 |isbn=978-0826119674 |name-list-style=amp}}</ref> Constructional apraxia is often caused by lesions of the inferior nondominant parietal lobe, and can be caused by brain injury, illness, tumor, or other condition that can result in a brain lesion.<ref name= Tonkonogy />
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