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===Male adrenoleukodystrophy phenotypes=== {| class="wikitable" |+ Male adrenoleukodystrophy phenotypes<ref name=scriver /> |- ! width=15% |Phenotype ! width=50% |Description ! width=15% |Onset ! width=20% |Approximate relative frequency |- | Childhood cerebral | Progressive neurodegenerative decline, leading to a vegetative state without treatment | 3β10 years | 31β35% |- | Adolescent | Similar to childhood cerebral, with a slower progression | 11β21 years | 4β7% |- | Adrenomyeloneuropathy (AMN) | Progressive [[neuropathy]], [[paraparesis]]; approximately 40% progress to cerebral involvement | 21β37 years | 40β46% |- | Adult cerebral | [[Dementia]], behavioral disturbances, similar progression to childhood cerebral form, but without preceding AMN phenotype | Adulthood | 2β5% |- | Olivo-ponto-cerebellar | Cerebral and [[brain stem]] involvement | Adolescence to adulthood | 1β2% |- | "[[Addison disease]] only" | Adrenal insufficiency | Before 7.5 years | Up to 50% in childhood, varies with age |- | Asymptomatic | No clinical presentation, further studies can reveal subclinical adrenal insufficiency or mild AMN phenotype | Most common phenotype in boys under four years of age | Proportion of asymptomatic patients decreases with age |}
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