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=== By place === ==== Seleucid Empire ==== * King [[Seleucus IV Philopator|Seleucus IV]] of [[Syria]] arranges for the exchange of his brother [[Antiochus IV Epiphanes|Antiochus]] for [[Demetrius I Soter|Demetrius]], the son of Seleucus IV, who has been a hostage in [[Roman Republic|Rome]] following the [[Treaty of Apamea]] in [[188 BC]]. However, Seleucus IV is assassinated by his chief minister [[Heliodorus (minister)|Heliodorus]] who then seizes the Syrian throne. * Antiochus manages to oust Heliodorus and takes advantage of Demetrius' captivity in Rome to seize the throne for himself under the name [[Antiochus IV Epiphanes]]. * During this period of uncertainty in Syria, the Egyptian ruler, Ptolemy VI, lays claim to [[Coele Syria]], [[Palestine (region)|Palestine]], and [[Phoenicia]], which the Seleucid king [[Antiochus III the Great|Antiochus III]] has previously conquered. Both the Syrian and Egyptian parties appeal to Rome for help, but the [[Roman Senate]] refuses to take sides. * [[Timarchus]] is appointed governor of [[Medes|Media]] in western [[Iran|Persia]] by Antiochus IV to deal with the growing threat from the [[Parthia]]ns while Timarchus' brother, Heracleides, becomes minister of the royal finances.
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