Editing Oxidative phosphorylation (section)

==== Hypoxia/anoxia tolerance ====
The naked mole rat ([[Naked mole-rat|''Heterocephalus glaber'']]) is a hypoxia-tolerant species that sleeps in deep burrows and in large colonies. The depth of these burrows reduces access to oxygen, and sleeping in large groups will deplete the area of oxygen quicker than usual, leading to hypoxia.<ref name="Pamenter_2018" /> The naked mole rat has the unique ability to survive low oxygen conditions for no less than several hours, and zero oxygen conditions for 18 minutes.<ref name="Eaton_2023">{{cite journal | vauthors = Eaton L, Wang T, Roy M, Pamenter ME | title = Naked Mole-Rat Cortex Maintains Reactive Oxygen Species Homeostasis During ''In Vitro'' Hypoxia or Ischemia and Reperfusion | journal = Current Neuropharmacology | volume = 21 | issue = 6 | pages = 1450–1461 | date = 2023 | pmid = 35339183 | pmc = 10324332 | doi = 10.2174/1570159X20666220327220929 }}</ref> One of the ways of combatting hypoxia in the brain is decreasing the reliance on oxygen for ATP production, achieved by decreased respiration rates and proton leak.<ref name="Pamenter_2018" />