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=== Adverse effects === In the short term, ingesting Ayahuasca can cause nausea, vomiting and diarrhea. These three effects, known as purging, are traditionally recognized to be a part of the spiritual experience of ayahuasca. Physiologically, vomiting is a result of increased [[serotonin]] circulating in the gut, which directly stimulates the [[vagus nerve]].<ref>{{Cite journal |last1=Fotiou |first1=Evgenia |last2=Gearin |first2=Alex K. |date=2019-10-01 |title=Purging and the body in the therapeutic use of ayahuasca |url=https://www.sciencedirect.com/science/article/abs/pii/S027795361930526X |journal=Social Science & Medicine |volume=239 |pages=112532 |doi=10.1016/j.socscimed.2019.112532 |pmid=31494522 |issn=0277-9536}}</ref> Other short-term side effects include [[Hypertension|increased blood pressure]] and [[tachycardia]]. Additionally, increased secretion of hormones like [[prolactin]], [[cortisone]], and [[growth hormone]] has been correlated with ayahuasca consumption.<ref>{{Cite journal |last1=Frecska |first1=Ede |last2=Bokor |first2=Petra |last3=Winkelman |first3=Michael |date=2016-03-02 |title=The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization |journal=Frontiers in Pharmacology |language=English |volume=7 |page=35 |doi=10.3389/fphar.2016.00035 |doi-access=free |pmid=26973523 |pmc=4773875 |issn=1663-9812}}</ref> Rarer side effects include [[dyspnea]], [[seizure]]s and [[serotonin syndrome]]. Ayahuasca is suspected of triggering [[psychosis]] in people with a predisposition to the condition, and there is a lack of safety information for Ayahuasca's possible effects on pregnancy and breastfeeding.<ref name=tox>{{cite journal |vauthors=White E, Kennedy T, Ruffell S, Perkins D, Sarris J |title=Ayahuasca and Dimethyltryptamine Adverse Events and Toxicity Analysis: A Systematic Thematic Review |journal=Int J Toxicol |volume=43 |issue=3 |pages=327β339 |date=2024 |pmid=38363085 |pmc=11088222 |doi=10.1177/10915818241230916 |type=Review}}</ref>
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