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===Drug testing=== {{Main|Cannabis drug testing}} THC and its 11-OH-THC and THC-COOH metabolites can be detected and quantified in blood, urine, hair, oral fluid or sweat using a combination of [[immunoassay]] and [[chromatographic]] techniques as part of a drug use testing program or in a forensic investigation.<ref>{{cite journal | vauthors = Schwilke EW, Schwope DM, Karschner EL, Lowe RH, Darwin WD, Kelly DL, Goodwin RS, Gorelick DA, Huestis MA | title = Delta9-tetrahydrocannabinol (THC), 11-hydroxy-THC, and 11-nor-9-carboxy-THC plasma pharmacokinetics during and after continuous high-dose oral THC | journal = Clinical Chemistry | volume = 55 | issue = 12 | pages = 2180–89 | date = December 2009 | pmid = 19833841 | pmc = 3196989 | doi = 10.1373/clinchem.2008.122119 }}</ref><ref>{{cite journal | vauthors = Röhrich J, Schimmel I, Zörntlein S, Becker J, Drobnik S, Kaufmann T, Kuntz V, Urban R | title = Concentrations of delta9-tetrahydrocannabinol and 11-nor-9-carboxytetrahydrocannabinol in blood and urine after passive exposure to Cannabis smoke in a coffee shop | journal = Journal of Analytical Toxicology | volume = 34 | issue = 4 | pages = 196–203 | date = May 2010 | pmid = 20465865 | doi = 10.1093/jat/34.4.196 | doi-access = free }}</ref><ref>{{cite book| vauthors = Baselt R |title=Disposition of Toxic Drugs and Chemicals in Man |edition=9th |publisher=Biomedical Publications |location=Seal Beach, CA |year=2011 |pages=1644–48}}</ref> There is ongoing research to create devices capable of detecting THC in breath.<ref name="cnn">{{cite news | vauthors = Wallace A |title=Testing drivers for cannabis is hard. Here's why |url=https://www.cnn.com/2020/01/02/business/cannabis-breathalyzers-are-coming-to-market/index.html |access-date=26 February 2020 |work=CNN Business |date=January 2, 2020 |archive-date=26 February 2020 |archive-url=https://web.archive.org/web/20200226030155/https://www.cnn.com/2020/01/02/business/cannabis-breathalyzers-are-coming-to-market/index.html |url-status=live }}</ref><ref>{{cite journal | vauthors = Mirzaei H, O'Brien A, Tasnim N, Ravishankara A, Tahmooressi H, Hoorfar M | title = Topical review on monitoring tetrahydrocannabinol in breath | journal = Journal of Breath Research | volume = 14 | issue = 3 | pages = 034002 | date = May 2020 | pmid = 31842004 | doi = 10.1088/1752-7163/ab6229 | bibcode = 2020JBR....14c4002M | s2cid = 209388839 }}</ref>
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