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===Research=== As of 2020, saffron constituents, such as [[crocin]], [[crocetin]], and [[safranal]], were under preliminary research for their potential to affect [[mental depression]].<ref>{{Cite journal|last1=Marx|first1=Wolfgang|last2=Lane|first2=Melissa|last3=Rocks|first3=Tetyana|last4=Ruusunen|first4=Anu|last5=Loughman|first5=Amy|last6=Lopresti|first6=Adrian|last7=Marshall|first7=Skye|last8=Berk|first8=Michael|last9=Jacka|first9=Felice|last10=Dean|first10=Olivia M|date=1 August 2019|title=Effect of saffron supplementation on symptoms of depression and anxiety: a systematic review and meta-analysis|url=https://academic.oup.com/nutritionreviews/article/77/8/557/5499264|journal=Nutrition Reviews|language=en|volume=77|issue=8|pages=557β571|doi=10.1093/nutrit/nuz023|pmid=31135916|issn=0029-6643}}</ref><ref>{{Cite journal|last1=Dai|first1=Lili|last2=Chen|first2=Lingyan|last3=Wang|first3=Wenjing|date=2020|title=Safety and Efficacy of Saffron (''Crocus sativus'' L.) for Treating Mild to Moderate Depression: A Systematic Review and Meta-analysis|url=https://dx.doi.org/10.1097%2FNMD.0000000000001118|journal=The Journal of Nervous and Mental Disease|language=en|volume=208|issue=4|pages=269β276|doi=10.1097/NMD.0000000000001118|pmid=32221179|s2cid=210119504}}</ref> Saffron has also been studied for its possible effect on cardiovascular [[Risk factor (epidemiology)|risk factor]]s,<ref>{{cite journal |last1=Pourmasoumi |first1=Makan |last2=Hadi |first2=Amir |last3=Najafgholizadeh |first3=Ameneh |last4=Kafeshani |first4=Marzieh |last5=Sahebkar |first5=Amirhossein |title=Clinical evidence on the effects of saffron (''Crocus sativus'' L.) on cardiovascular risk factors: A systematic review meta-analysis |journal=Pharmacological Research |date=1 January 2019 |volume=139 |pages=348β359 |doi=10.1016/j.phrs.2018.11.038|pmid=30502528 |s2cid=54482370 }}</ref> and in [[erectile dysfunction]].<ref>{{cite journal |last1=Borrelli |first1=Francesca |last2=Colalto |first2=Cristiano |last3=Delfino |first3=Domenico V. |last4=Iriti |first4=Marcello |last5=Izzo |first5=Angelo A. |title=Herbal Dietary Supplements for Erectile Dysfunction: A Systematic Review and Meta-Analysis |journal=Drugs |date=April 2018 |volume=78 |issue=6 |pages=643β673 |doi=10.1007/s40265-018-0897-3 |pmid=29633089|s2cid=4759438 }}</ref>
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