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===Detection in body fluids=== Pseudoephedrine may be quantified in blood, plasma, or urine to monitor any possible performance-enhancing use by athletes, confirm a diagnosis of poisoning, or to assist in a medicolegal death investigation. Some commercial [[immunoassay]] screening tests directed at the amphetamines cross-react appreciably with pseudoephedrine, but [[Chromatography|chromatographic]] techniques can easily distinguish pseudoephedrine from other phenethylamine derivatives. Blood or plasma pseudoephedrine concentrations are typically in the 50 to 300{{nbsp}}ΞΌg/L range in persons taking the drug therapeutically, 500 to 3,000{{nbsp}}ΞΌg/L in people with substance use disorder involving pseudoephedrine or poisoned patients, and 10 to 70{{nbsp}}mg/L in cases of acute fatal [[overdose]].<ref name="BolandReinLew2003">{{cite journal | vauthors = Boland DM, Rein J, Lew EO, Hearn WL | title = Fatal cold medication intoxication in an infant | journal = Journal of Analytical Toxicology | volume = 27 | issue = 7 | pages = 523β526 | date = October 2003 | pmid = 14607011 | doi = 10.1093/jat/27.7.523 | doi-access = free | title-link = doi }}</ref><ref name="Baselt2008">{{cite book | vauthors = Baselt R | url = http://www.biomedicalpublications.com/ | title = Disposition of Toxic Drugs and Chemicals in Man | edition = 8th | publisher = Biomedical Publications | location = Foster City, California | year = 2008 | pages = 1344β1346 | access-date = 19 August 2010 | archive-date = 4 December 2020 | archive-url = https://web.archive.org/web/20201204114016/http://www.biomedicalpublications.com/ | url-status = live }}</ref>
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