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===Anatomical defects and trauma=== Fifteen per cent of women who have experienced three or more recurring miscarriages have some anatomical defect that prevents the pregnancy from being carried for the entire term.{{sfn|Hoffman|page=181}} The structure of the uterus affects the ability to carry a child to term. Anatomical differences are common and can be congenital.<ref>{{Cite journal |last1=Qian |first1=Liang |last2=Ding |first2=Jiashan |last3=Shi |first3=Lan |last4=Yu |first4=Qing |last5=Zhu |first5=Jiawei |last6=Huang |first6=Anfeng |date=2023-12-04 |title=Analysis of hemi-uterus pregnancy outcomes in uterine malformations: a retrospective observational study |journal=BMC Pregnancy and Childbirth |volume=23 |issue=1 |pages=836 |doi=10.1186/s12884-023-06136-w |doi-access=free |pmid=38049742 |pmc=10696795 |issn=1471-2393}}</ref> {| class="wikitable" !Type of uterine<br>structure !Miscarriage rate<br>associated with defect !References |- |[[Bicornate uterus]] |40β79% |{{sfn|Hoffman|page=181β182}}<ref name="auto7"/> |- |[[Septate uterus|Septate]] or [[Unicornuate uterus|unicornate]] |34β88% |{{sfn|Hoffman|page=181β182}} |- |[[Arcuate uterus|Arcuate]] |Unknown |{{sfn|Hoffman|page=181β182}} |- |[[Uterus didelphys|Didelphys]] |40% |{{sfn|Hoffman|page=181β182}} |- |[[Uterine fibroid|Fibroids]] |Unknown |<ref name="NHS-Miscarriage-Causes"/> |- |} In some women, [[cervical incompetence]] or cervical insufficiency occurs with the inability of the cervix to stay closed during the entire pregnancy.<ref name="American College of Obstetricians and 372β9"/><ref name="NHS-Miscarriage-Causes"/> It does not cause first-trimester miscarriages. In the second trimester, it is associated with an increased risk of miscarriage. It is identified after a premature birth has occurred at about 16β18 weeks into the pregnancy.{{sfn|Hoffman|page=181}} During the second trimester, major trauma can result in a miscarriage.{{sfn|Hoffman|page=172}}
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