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===European royalty=== {{main|Haemophilia in European royalty}} [[File:Erbgang Bluterkrankheit.svg|thumb|upright=1.8|Haemophilia in European royalty]] Haemophilia has featured prominently [[Haemophilia in European royalty|in European royalty]] and thus is sometimes known as 'the royal disease'. [[Queen Victoria]] passed the mutation for haemophilia B<ref>{{cite news|author=Michael Price|title=Case Closed: Famous Royals Suffered From Hemophilia|url=http://sciencenow.sciencemag.org/cgi/content/full/2009/1008/2|newspaper=ScienceNOW Daily News|publisher=AAAS|date=8 October 2009|access-date=9 October 2009|url-status=dead|archive-url=https://web.archive.org/web/20091012020300/http://sciencenow.sciencemag.org/cgi/content/full/2009/1008/2|archive-date=12 October 2009}}</ref><ref>{{cite journal|author=Evgeny I. Rogaev|title=Genotype Analysis Identifies the Cause of the 'Royal Disease'|journal=Science|volume=326|issue=5954|pages=817|date=8 October 2009|display-authors=etal|doi=10.1126/science.1180660|pmid=19815722|bibcode=2009Sci...326..817R|s2cid=206522975|doi-access=free}}</ref> to her son [[Leopold, Duke of Albany|Leopold]] and, through two of her daughters, Alice and Beatrice, to various royals across the continent, including the royal families of [[House of Bourbon|Spain]], [[Hohenzollern|Germany]], and [[Romanov|Russia]]. In Russia, [[Alexei Nikolaevich, Tsarevich of Russia|Tsarevich Alexei]], the son and heir of [[Nicholas II of Russia|Tsar Nicholas II]], famously had haemophilia, which he had inherited from his mother, [[Alexandra Feodorovna (Alix of Hesse)|Empress Alexandra]], one of Queen Victoria's granddaughters. The haemophilia of Alexei would result in the rise to prominence of the Russian mystic [[Grigori Rasputin]] at the imperial court.<ref>{{cite book|last=Massie|first=Robert K.|title=Nicholas and Alexandra: The Classic Account of the Fall of the Romanov Dynasty |publisher=[[Random House]]|date=2011|page=532|isbn=978-0-307-78847-4}}</ref> It was claimed that Rasputin was successful at treating Tsarevich Alexei's haemophilia. At the time, a common treatment administered by professional doctors was to use [[aspirin]], which worsened rather than lessened the problem. It is believed that, by simply advising against the medical treatment, Rasputin could bring visible and significant improvement to the condition of Tsarevich Alexei.<ref>{{cite book|last=Jeffreys|first=Diarmud|title=Aspirin: The Remarkable Story of a Wonder Drug|publisher=[[Bloomsbury Publishing]]|date=2008|page=121|isbn=978-1-59691-816-0}}</ref> In Spain, Queen Victoria's youngest daughter, [[Princess Beatrice of the United Kingdom|Princess Beatrice]], had a daughter [[Victoria Eugenie of Battenberg]], who later became Queen of Spain. Two of her sons were haemophiliacs and both died from minor car accidents. Her eldest son, [[Alfonso, Prince of Asturias (1907β1938)|Prince Alfonso of Spain, Prince of Asturias]], died at the age of 31 from internal bleeding after his car hit a telephone booth.<ref>{{Cite web|title=Tragic Drama Under the Miami Moon|url=http://www.biscaynetimes.com/index.php?option=com_content&id=264:tragic-drama-under-the-miami-moon&Itemid=162|access-date=24 June 2020|work=Biscayne times |archive-date=25 June 2020|archive-url=https://web.archive.org/web/20200625034408/http://www.biscaynetimes.com/index.php?option=com_content&id=264:tragic-drama-under-the-miami-moon&Itemid=162 |url-status=dead}}</ref> Her youngest son, [[Infante Gonzalo of Spain|Infante Gonzalo]], died at age 19 from abdominal bleeding following a minor car accident in which he and his sister hit a wall while avoiding a cyclist. Neither appeared injured or sought immediate medical care and Gonzalo died two days later from internal bleeding.<ref>{{Cite news|title=AUTO CRASH FATAL TO SPANISH PRINCE; Don Gonzalo, 19, Succumbs to Hemophilia After Collision in Austrian Village. INFANTA BEATRIZ DRIVING Swerved Car to Avoid Hitting Bicyclist β Ex-King Present at Son's Bedside.| work=The New York Times |url=http://timesmachine.nytimes.com/timesmachine/1934/08/14/93638215.html |access-date=24 June 2020|language=en}}</ref>
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