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==Folk medicine and safety concerns== Extracts and other preparations of ''E. arvense'' have served as [[traditional medicine|herbal remedies]], with records dating over centuries.<ref name=drugs/><ref name="NIH">{{cite web |url=https://www.nlm.nih.gov/medlineplus/druginfo/natural/843.html|title=Horsetail|publisher=MedlinePlus, US National Library of Medicine, National Institutes of Health|date=8 December 2017|access-date=14 November 2013}}</ref><ref name="sarris">{{cite journal|pmc=5295114|year=2017|last1=Dragos|first1=D|title=Phytomedicine in Joint Disorders|journal=Nutrients|volume=9|issue=1|pages=70|last2=Gilca|first2=M|last3=Gaman|first3=L|last4=Vlad|first4=A|last5=Iosif|first5=L|last6=Stoian|first6=I|last7=Lupescu|first7=O|doi=10.3390/nu9010070|pmid=28275210|doi-access=free}}</ref> In 2009, the [[European Food Safety Authority]] concluded there was no evidence for the supposed [[health claim|health effects]] of ''E. arvense'', such as for invigoration, weight control, skincare, hair health or bone health.<ref name ="efsa">{{Cite journal|title=Scientific opinion on the substantiation of health claims related to ''Equisetum arvense'' L. and invigoration of the body (ID 2437), maintenance of skin (ID 2438), maintenance of hair (ID 2438), maintenance of bone (ID 2439), and maintenance or achievement of a normal body weight (ID 2783) pursuant to Article 13 of Regulation (EC) No 1924/2006|journal=EFSA Journal|volume=7|issue=10|pages=1289|publisher=[[European Food Safety Authority]]|doi=10.2903/j.efsa.2009.1289|year=2009|doi-access=free}}</ref> {{As of|2018}}, there is insufficient scientific evidence for its effectiveness as a medicine to treat any human condition.<ref name=drugs/><ref name=sarris/><ref name=efsa/> ''E. arvense'' contains [[thiaminase]], which metabolizes the [[B vitamins|B vitamin]], [[thiamine]], potentially causing [[thiamine deficiency]] and associated [[hepatotoxicity|liver damage]], if taken chronically.<ref name=drugs/><ref name=NIH/> Horsetail might produce a [[diuresis|diuretic effect]].<ref name=drugs/><ref name=NIH/> Further, its safety for oral consumption has not been sufficiently evaluated and it may be [[toxicity|toxic]], especially to children and pregnant women.<ref name=drugs/>
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