Editing Diarrhea (section)

==Pathophysiology==
{| class="wikitable" style = "float: right; margin-left:15px; text-align:center"
|+ Ion transporters targeted by enteric infections <ref>{{cite journal | vauthors = Das S, Jayaratne R, Barrett KE | title = The Role of Ion Transporters in the Pathophysiology of Infectious&nbsp;Diarrhea | journal = Cellular and Molecular Gastroenterology and Hepatology | volume = 6 | issue = 1 | pages = 33–45 | date = 2018 | pmid = 29928670 | pmc = 6007821 | doi = 10.1016/j.jcmgh.2018.02.009 }}</ref>
! Function &nbsp;!! Transporter
|-
|Absorption|| [[NHE]], [[SGLT1]], [[ENaC]], [[Downregulated-in-adenoma|DRA]]
|-
|Secretion||[[CaCC]], [[NKCC1]], [[CFTR]]
|-
|Absorption and secretion
||[[Sodium potassium ATPase]]
|}

===Evolution===
According to two researchers, [[Randolph M. Nesse|Nesse]] and [[George C. Williams (biologist)|Williams]], diarrhea may function as an evolved expulsion defense mechanism. As a result, if it is stopped, there might be a delay in recovery.<ref>{{cite book | vauthors = Williams G, Nesse RM |title=Why we get sick: the new science of Darwinian medicine |publisher=[[Vintage Books]] |location=New York |year=1996 |pages=36–38 |isbn=978-0-679-74674-4 }}</ref> They cite in support of this argument research published in 1973 that found that treating ''[[Shigella]]'' with the anti-diarrhea drug (Co-phenotrope, [[Lomotil]]) caused people to stay [[fever]]ish twice as long as those not so treated. The researchers indeed themselves observed that: "Lomotil may be contraindicated in shigellosis. Diarrhea may represent a defense mechanism".<ref>{{cite journal | vauthors = DuPont HL, Hornick RB | title = Adverse effect of lomotil therapy in shigellosis | journal = JAMA | volume = 226 | issue = 13 | pages = 1525–8 | date = December 1973 | pmid = 4587313 | doi = 10.1001/jama.226.13.1525 }}</ref>