Editing Chemotherapy (section)

=== Secondary neoplasm ===
Development of secondary neoplasia after successful chemotherapy or radiotherapy treatment can occur. The most common [[secondary neoplasm]] is secondary acute myeloid leukemia, which develops primarily after treatment with alkylating agents or topoisomerase inhibitors.<ref>{{Cite book |title=Secondary neoplasias following chemotherapy, radiotherapy and immunosuppression |date=2000 |publisher=Karger |isbn=9783318006155 |volume=55 |location=Basel |oclc=606559421}}</ref> Survivors of [[childhood cancer]] are more than 13 times as likely to get a [[secondary neoplasm]] during the 30 years after treatment than the general population.<ref>{{cite journal | vauthors = Hijiya N, Hudson MM, Lensing S, Zacher M, Onciu M, Behm FG, Razzouk BI, Ribeiro RC, Rubnitz JE, Sandlund JT, Rivera GK, Evans WE, Relling MV, Pui CH | title = Cumulative incidence of secondary neoplasms as a first event after childhood acute lymphoblastic leukemia | journal = JAMA | volume = 297 | issue = 11 | pages = 1207–15 | date = March 2007 | pmid = 17374815 | doi = 10.1001/jama.297.11.1207 | doi-access = free }}</ref> Not all of this increase can be attributed to chemotherapy.