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=== Small RNA === The list of [[small RNA]]s involved in the control of bacterial virulence in ''S. aureus'' is growing. This can be facilitated by factors such as increased biofilm formation in the presence of increased levels of such small RNAs.<ref name=Kim14>{{cite journal | vauthors = Kim S, Reyes D, Beaume M, Francois P, Cheung A | title = Contribution of teg49 small RNA in the 5' upstream transcriptional region of sarA to virulence in ''Staphylococcus aureus'' | journal = Infection and Immunity | volume = 82 | issue = 10 | pages = 4369β79 | date = October 2014 | pmid = 25092913 | pmc = 4187880 | doi = 10.1128/iai.02002-14 }}</ref> For example, [[RNAIII]],<ref>{{cite journal | vauthors = Chevalier C, Boisset S, Romilly C, Masquida B, Fechter P, Geissmann T, Vandenesch F, Romby P | title = ''Staphylococcus aureus'' RNAIII binds to two distant regions of coa mRNA to arrest translation and promote mRNA degradation | journal = PLOS Pathogens | volume = 6 | issue = 3 | pages = e1000809 | date = March 2010 | pmid = 20300607 | pmc = 2837412 | doi = 10.1371/journal.ppat.1000809 | doi-access = free }}</ref> [[SprD]],<ref>{{cite journal | vauthors = Chabelskaya S, Gaillot O, Felden B | title = A ''Staphylococcus aureus'' small RNA is required for bacterial virulence and regulates the expression of an immune-evasion molecule | journal = PLOS Pathogens | volume = 6 | issue = 6 | pages = e1000927 | date = June 2010 | pmid = 20532214 | pmc = 2880579 | doi = 10.1371/journal.ppat.1000927 | doi-access = free }}</ref> SprC,<ref>{{cite journal | vauthors = Le Pabic H, Germain-Amiot N, Bordeau V, Felden B | title = A bacterial regulatory RNA attenuates virulence, spread and human host cell phagocytosis | journal = Nucleic Acids Research | volume = 43 | issue = 19 | pages = 9232β48 | date = October 2015 | pmid = 26240382 | pmc = 4627067 | doi = 10.1093/nar/gkv783 }}</ref><ref>{{cite journal | vauthors = Mauro T, Rouillon A, Felden B | title = Insights into the regulation of small RNA expression: SarA represses the expression of two sRNAs in ''Staphylococcus aureus'' | journal = Nucleic Acids Research | volume = 44 | issue = 21 | pages = 10186β200 | date = December 2016 | pmid = 27596601 | pmc = 5137438 | doi = 10.1093/nar/gkw777 }}</ref> [[Rsa RNA|RsaE]],<ref>{{cite journal | vauthors = Bohn C, Rigoulay C, Chabelskaya S, Sharma CM, Marchais A, Skorski P, BorezΓ©e-Durant E, Barbet R, Jacquet E, Jacq A, Gautheret D, Felden B, Vogel J, Bouloc P | title = Experimental discovery of small RNAs in ''Staphylococcus aureus'' reveals a riboregulator of central metabolism | journal = Nucleic Acids Research | volume = 38 | issue = 19 | pages = 6620β36 | date = October 2010 | pmid = 20511587 | pmc = 2965222 | doi = 10.1093/nar/gkq462 }}</ref> SprA1,<ref>{{cite journal | vauthors = Sayed N, Jousselin A, Felden B | title = A cis-antisense RNA acts in trans in ''Staphylococcus aureus'' to control translation of a human cytolytic peptide | journal = Nature Structural & Molecular Biology | volume = 19 | issue = 1 | pages = 105β112 | date = December 2011 | pmid = 22198463 | doi = 10.1038/nsmb.2193 | s2cid = 8217681 | url = https://www.hal.inserm.fr/inserm-00696345/file/NSMBfinal.pdf }}</ref> SSR42,<ref>{{cite journal | vauthors = Morrison JM, Miller EW, Benson MA, Alonzo F, Yoong P, Torres VJ, Hinrichs SH, Dunman PM | title = Characterization of SSR42, a novel virulence factor regulatory RNA that contributes to the pathogenesis of a ''Staphylococcus aureus'' USA300 representative | journal = Journal of Bacteriology | volume = 194 | issue = 11 | pages = 2924β38 | date = June 2012 | pmid = 22493015 | pmc = 3370614 | doi = 10.1128/JB.06708-11 }}</ref> ArtR,<ref>{{cite journal | vauthors = Xue T, Zhang X, Sun H, Sun B | title = ArtR, a novel sRNA of ''Staphylococcus aureus'', regulates Ξ±-toxin expression by targeting the 5' UTR of sarT mRNA | journal = Medical Microbiology and Immunology | volume = 203 | issue = 1 | pages = 1β12 | date = February 2014 | pmid = 23955428 | doi = 10.1007/s00430-013-0307-0 | s2cid = 18371872 }}</ref> [[SprX small RNA|SprX]], [[Teg49 small RNA|Teg49]], <ref name=Kim14/> and IsrR.<ref>{{cite journal | vauthors = Coronel-Tellez RH, Pospiech M, Barrault M, Liu W, Bordeau V, Vasnier C, Felden B, Sargueil B, Bouloc P | title = sRNA-controlled iron sparing response in Staphylococci | journal = Nucleic Acids Research | volume = 50 | issue = 15 | pages = 8529β8546 | date = August 2022 | pmid = 35904807| pmc = 9410917 | doi = 10.1093/nar/gkac648 }}</ref>
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