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====Type 1 diabetes==== {{Main|Diabetes mellitus type 1}} [[Diabetes mellitus type 1]] is a chronic [[autoimmune disease]] in which the [[immune system]] attacks the insulin-secreting beta cells of the pancreas.<ref name=Ganongs2019DM>{{Cite book|title=Ganong's review of medical physiology|publisher=McGraw-Hill Education |first1=Kim E. |last1=Barrett |first2=Susan M. |last2=Barman |first3=Heddwen L. |last3=Brooks |first4=Jason X.-J. |last4=Yuan |first5=William F. |last5=Ganong |isbn=978-1-260-12240-4|edition=26th|location=New York|oclc=1076268769|year=2019|pages=440β441|section=Hypoglycaemia & Diabetes Mellitus in Humans}}</ref> Insulin is needed to keep [[blood sugar]] levels within optimal ranges, and its lack can lead to [[hyperglycemia|high blood sugar]]. As an untreated chronic condition, complications including accelerated [[vascular disease]], [[diabetic retinopathy]], [[diabetic nephropathy|kidney disease]] and [[diabetic neuropathy|neuropathy]] can result.<ref name=Ganongs2019DM /> In addition, if there is not enough insulin for glucose to be used within cells, the medical emergency [[diabetic ketoacidosis]], which is often the first symptom that a person with type 1 diabetes may have, can result.{{sfn|Davidson's|2018|p=735}} Type 1 diabetes can develop at any age but is most often diagnosed before age 40.<ref name=Ganongs2019DM /> For people living with type 1 diabetes, insulin injections are critical for survival.<ref name=Ganongs2019DM /> An experimental procedure to treat type 1 diabetes is [[pancreas transplantation]] or isolated [[islet cell transplantation|transplantation of islet cells]] to supply a person with functioning beta cells.<ref name=Ganongs2019DM />
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