Editing Hepatitis (section)

=== Other ===
{{Main|Neonatal hepatitis}}
Hepatitis can also occur in neonates and is attributable to a variety of causes, some of which are not typically seen in adults.<ref name="Biliary disease in infancy">{{cite journal |author1=Samyn, M |author2=Mieli-Vergani, G  |date=November 2015 |title=Liver and Biliary Disease in Infancy |journal=Medicine |volume=43 |issue=11 |pages=625–630 |doi= 10.1016/j.mpmed.2015.08.008}}</ref> Congenital or perinatal infection with the hepatitis viruses, [[Toxoplasma gondii|toxoplasma]], [[rubella]], [[cytomegalovirus]], and [[syphilis]] can cause neonatal hepatitis.<ref name="Biliary disease in infancy" /> Structural abnormalities such as [[biliary atresia]] and [[choledochal cysts]] can lead to [[Cholestasis|cholestatic liver injury]] leading to neonatal hepatitis.<ref name="Biliary disease in infancy" /> [[Inborn error of metabolism|Metabolic diseases]] such as [[Glycogen storage disease|glycogen storage disorders]] and [[Lysosomal storage disease|lysosomal storage disorders]] are also implicated.<ref name="Biliary disease in infancy" /> Neonatal hepatitis can be [[Idiopathy|idiopathic]], and in such cases, biopsy often shows large multinucleated cells in the liver tissue.<ref>{{cite journal |last=Roberts |first=Eve A. |date=2003-10-01 |title=Neonatal hepatitis syndrome |journal=Seminars in Neonatology |volume=8 |issue=5 |pages=357–374 |doi=10.1016/S1084-2756(03)00093-9 |issn=1084-2756 |pmid=15001124}}</ref> This disease is termed giant cell hepatitis and may be associated with viral infection, autoimmune disorders, and drug toxicity.<ref>{{cite book |last1=Sokol |first1=Ronald J. |last2=Narkewicz |first2=Michael R. |chapter=Chapter 22: Liver & Pancreas |editor1-last=Hay |editor1-first=William W. |display-editors=etal |title=Current diagnosis & treatment: pediatrics |edition=21st |location=New York |publisher=McGraw-Hill Medical |isbn=978-0-07-177970-8 |chapter-url=http://www.accessmedicine.com/content.aspx?aID=56821699 |access-date=2 December 2013 |url-status=live |archive-url=https://web.archive.org/web/20131210093945/http://www.accessmedicine.com/content.aspx?aID=56821699 |archive-date=10 December 2013 |date=2012-06-21 }}</ref><ref>{{cite journal |last=Alexopoulou |first=Alexandra |author2=Deutsch, Melanie |author3=Ageletopoulou, Johanna |author4=Delladetsima, Johanna K. |author5=Marinos, Evangelos |author6=Kapranos, Nikiforos |author7=Dourakis, Spyros P. |date=May 2003 |title=A fatal case of postinfantile giant cell hepatitis in a patient with chronic lymphocytic leukaemia |journal=European Journal of Gastroenterology & Hepatology |volume=15 |issue=5 |pages=551–555 |doi=10.1097/01.meg.0000050026.34359.7c |pmid=12702915}}</ref>