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=== Set-Point Theory === {{see also|Energy homeostasis#Imbalance}} The Set-Point Theory, first introduced in 1953, postulated that each body has a preprogrammed fixed weight, with regulatory mechanisms to compensate. This theory was quickly adopted and used to explain failures in developing effective and sustained weight loss procedures. A 2019 systematic review of multiple weight change procedures, including alternate day fasting and time-restricted feeding but also exercise and overeating, found systematic "energetic errors" for all these procedures. This shows that the body cannot precisely compensate for errors in energy/calorie intake, countering the Set-Point Theory and potentially explaining both [[weight loss]] and weight gain such as [[obesity]]. This review was conducted on short-term studies, therefore such a mechanism cannot be excluded in the long term, as evidence is currently lacking on this timeframe.<ref>{{cite journal | vauthors = Levitsky DA, Sewall A, Zhong Y, Barre L, Shoen S, Agaronnik N, LeClair JL, Zhuo W, Pacanowski C | display-authors = 6 | title = Quantifying the imprecision of energy intake of humans to compensate for imposed energetic errors: A challenge to the physiological control of human food intake | journal = Appetite | volume = 133 | pages = 337β343 | date = February 2019 | pmid = 30476522 | doi = 10.1016/j.appet.2018.11.017 | s2cid = 53712116 }}</ref>
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