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=== Taste === Cats have about 470 [[taste bud]]s, compared to more than 9,000 on the human tongue.<ref name="sch">{{cite web |title=Do cats have a sense of taste? |url= http://www.cathealth.com/nutrition/do-cats-have-a-sense-of-taste |website=CatHealth.com |last=Schelling |first=Christianne |url-status=live |archive-url= https://web.archive.org/web/20160128163535/http://www.cathealth.com/nutrition/do-cats-have-a-sense-of-taste|archive-date=28 January 2016}}</ref> Domestic and wild cats share a [[Taste receptor#Loss of function|taste receptor gene mutation]] that keeps their sweet taste buds from binding to sugary molecules, leaving them with no ability to taste [[sweetness]].<ref>{{Citation |last1=Jiang |first1=Peihua |last2=Josue |first2=Jesusa |last3=Li |first3=Xia |last4=Glaser |first4=Dieter |last5=Li |first5=Weihua |last6=Brand |first6=Joseph G. |last7=Margolskee |first7=Robert F. |last8=Reed |first8=Danielle R. |last9=Beauchamp |first9=Gary K. |title=Major taste loss in carnivorous mammals |journal=PNAS |volume=13 |issue=109 |pages=4956β4961 |date=12 March 2012 |doi=10.1073/pnas.1118360109 |pmid=22411809 |pmc=3324019 |doi-access=free}}</ref> But they do have taste bud receptors specialized for [[acid]]s, [[amino acid]]s such as the constituents of protein, and bitter tastes.<ref name="Bradshaw2006">{{cite journal |volume=136 |issue=7 |pages=1927Sβ1931 |last=Bradshaw |first=John W. S. |title=The evolutionary basis for the feeding behavior of domestic dogs (''Canis familiaris'') and cats (''Felis catus'') |journal=Journal of Nutrition |date=1 July 2006 |pmid=16772461 |doi=10.1093/jn/136.7.1927S |doi-access=free}}</ref> Cats taste buds possess the receptors needed to detect [[umami]]. However, these receptors contain molecular changes that make them taste umami differently from humans. In humans, they detect the amino acids [[glutamic acid]] and [[aspartic acid]]; but in cats, they instead detect [[inosine monophosphate]] and [[histidine]].<ref name="McGrane Gibbs Hernangomez de Alvaro Dunlop">{{cite journal |last1=McGrane |first1=Scott J. |last2=Gibbs |first2=Matthew |last3=Hernangomez de Alvaro |first3=Carlos |last4=Dunlop |first4=Nicola |last5=Winnig |first5=Marcel |last6=Klebansky |first6=Boris |last7=Waller |first7=Daniel |title=Umami taste perception and preferences of the domestic cat (''Felis catus''), an obligate carnivore |journal=Chemical Senses |volume=48 |date=1 January 2023 |issn=0379-864X |doi=10.1093/chemse/bjad026 |pmid=37551788 |pmc=10468298}}</ref> These molecules are particularly enriched in [[tuna]].<ref name="McGrane Gibbs Hernangomez de Alvaro Dunlop" /> Researchers argue why cats find tuna so [[Palatability|palatable]]: "the specific combination of the high IMP and free histidine contents of tuna, which produces a strong umami taste synergy that is highly preferred by cats."<ref name="McGrane Gibbs Hernangomez de Alvaro Dunlop" /> One researcher said, "I think umami is as important for cats as sweet is for humans."<ref name="Science Tuna Cat">{{cite journal |last=Grimm |first=David |title=Why do cats love tuna so much? |journal=[[Science (journal)|Science]] |volume=381 |date=1 October 2023 |issue=6661 |issn=0036-8075 |doi=10.1126/science.adk5725 |page=935|pmid=37651517 |bibcode=2023Sci...381..935G |s2cid=261395204}}</ref> Cats distinctly prefer food temperature around {{convert|38|C|F|abbr=on}}, similar to a fresh kill. Some cats reject cold food, which would signal to the cat that the prey is long dead and therefore possibly toxic or decomposing.<ref name="sch" />
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