Editing Zoonosis (section)

== Use in vaccines ==
The first vaccine against smallpox by [[Edward Jenner]] in 1800 was by infection of a zoonotic bovine virus which caused a disease called [[cowpox]].<ref>{{cite web|date=21 February 2021|title=History of Smallpox {{!}} Smallpox {{!}} CDC|url=https://www.cdc.gov/smallpox/history/history.html|access-date=21 September 2021|website=www.cdc.gov|archive-date=14 June 2020|archive-url=https://web.archive.org/web/20200614213232/https://www.cdc.gov/smallpox/history/history.html|url-status=live}}</ref> Jenner had noticed that milkmaids were resistant to smallpox. Milkmaids contracted a milder version of the disease from infected cows that conferred cross immunity to the human disease. Jenner abstracted an infectious preparation of 'cowpox' and subsequently used it to inoculate persons against smallpox. As a result of vaccination, smallpox has been eradicated globally, and mass inoculation against this disease ceased in 1981.<ref>{{cite web|url=https://www.cdc.gov/smallpox/history/smallpox-origin.html|title=The Spread and Eradication of Smallpox &#124; Smallpox &#124; CDC|date=19 February 2019}}</ref> There are a variety of vaccine types, including traditional inactivated pathogen vaccines, [[subunit vaccine]]s, [[Attenuated vaccine|live attenuated vaccines]]. There are also new vaccine technologies such as viral vector vaccines and [[MRNA vaccine|DNA/RNA vaccines]], which include many of the [[COVID-19 vaccine]]s.<ref>{{Cite web |last=Mayo Clinic Staff |date=4 November 2023 |title=Different types of COVID-19 vaccines: How they work |url=https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/different-types-of-covid-19-vaccines/art-20506465 |access-date=4 April 2024 |website=Mayo Clinic}}</ref>