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=== Discovery === ''B. pertussis'' was discovered in 1906 by [[Jules Bordet]] and [[Octave Gengou]] (the bacterium is subsequently named ''Bordetella pertussis'' in honour of Jules Bordet). They were able to successfully culture ''B. pertussis'' and went on to develop the first inactivated [[whole-cell vaccine]] in 1912, followed by other researchers in 1913 and 1914. These early vaccines had limited effectiveness. In the 1920s, [[Louis W. Sauer]] developed a vaccine for whooping cough at [[NorthShore University HealthSystem#Evanston Hospital|Evanston Hospital]]. In 1925 Danish physician Thorvald Madsen was the first to test a whole-cell vaccine on a wide scale. Madsen used the vaccine to control outbreaks in the [[Faroe Islands]] in the North Sea, however, two children died shortly after receiving the vaccine.<ref name="Baker_2004">{{cite journal | vauthors = Baker JP, Katz SL | title = Childhood vaccine development: an overview | journal = Pediatric Research | volume = 55 | issue = 2 | pages = 347β56 | date = February 2004 | pmid = 14630981 | doi = 10.1203/01.PDR.0000106317.36875.6A | doi-access = free }}</ref><ref>{{Cite web |title=Pertussis |url=https://www.museumofhealthcare.ca/explore/exhibits/vaccinations/pertussis.html |access-date=2024-11-04 |website=Museum of Health Care}}</ref><ref>{{Citation |last=Vaccines |first=Institute of Medicine (US) Committee to Review the Adverse Consequences of Pertussis and Rubella |title=Pertussis and Rubella Vaccines: A Brief Chronology |date=1991 |work=Adverse Effects of Pertussis and Rubella Vaccines: A Report of the Committee to Review the Adverse Consequences of Pertussis and Rubella Vaccines |url=https://www.ncbi.nlm.nih.gov/books/NBK234365/ |access-date=2024-11-04 |publisher=National Academies Press (US) |language=en |last2=Howson |first2=Christopher P. |last3=Howe |first3=Cynthia J. |last4=Fineberg |first4=Harvey V.}}</ref>
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