Editing Streptococcus (section)

==Genomics==
[[File:Streptococcus gene overlap.png|thumb|Common and species-specific genes among ''[[Streptococcus sanguinis]]'', ''[[Streptococcus mutans|S. mutans]]'', and ''[[Streptococcus pneumoniae|S. pneumoniae]]''. Modified after Xu et al. (2007)<ref name="Xu2007">{{cite journal | vauthors = Xu P, Alves JM, Kitten T, Brown A, Chen Z, Ozaki LS, Manque P, Ge X, Serrano MG, Puiu D, Hendricks S, Wang Y, Chaplin MD, Akan D, Paik S, Peterson DL, Macrina FL, Buck GA | display-authors = 6 | title = Genome of the opportunistic pathogen Streptococcus sanguinis | journal = Journal of Bacteriology | volume = 189 | issue = 8 | pages = 3166–3175 | date = April 2007 | pmid = 17277061 | pmc = 1855836 | doi = 10.1128/JB.01808-06 }}</ref> ]]
The genomes of hundreds of species have been sequenced.<ref>{{cite web | url = http://patricbrc.org/portal/portal/patric/Taxon?cType=taxon&cId=1301 | title = Streptococcus | archive-url =https://web.archive.org/web/20130310052630/http://patricbrc.org/portal/portal/patric/Taxon?cType=taxon&cId=1301 | archive-date=2013-03-10 | work = PATRIC | publisher = Virginia Bioinformatics Institute | location = Blacksburg, VA }}</ref> Most ''Streptococcus'' genomes are 1.8 to 2.3 Mb in size and encode 1,700 to 2,300 proteins. Some important genomes are listed in the table.<ref name="Ferretti2004">{{cite journal | vauthors = Ferretti JJ, Ajdic D, McShan WM | title = Comparative genomics of streptococcal species | journal = The Indian Journal of Medical Research | volume = 119 | issue = Suppl | pages = 1–6 | date = May 2004 | pmid = 15232152 }}</ref> The four species shown in the table (''S. pyogenes, S. agalactiae, S. pneumoniae'', and ''S. mutans'') have an average pairwise protein sequence identity of about 70%.<ref name="Ferretti2004" />

{| class="wikitable"
!feature !! ''S. pyogenes'' !!''S. agalactiae''!!''S. pneumoniae''!! ''S. mutans''
|-
| [[base pair]]s || 1,852,442|| 2,211,488 ||2,160,837 ||2,030,921
|-
| [[Open reading frame|ORFs]] || 1792 ||2118 ||2236 ||1963
|-
| [[prophage]]s || yes ||no ||no ||no
|}