Editing Salmonella (section)

=== Clinical symptoms ===
Salmonellosis is known to be able to cause [[back pain]] or [[spondylosis]].  It can manifest as five clinical patterns: gastrointestinal tract infection, enteric fever, bacteremia, local infection, and the chronic reservoir state. The initial symptoms are nonspecific fever, weakness, and myalgia among others. In the bacteremia state, it can spread to any parts of the body and this induces localized infection or it forms abscesses. The forms of localized ''Salmonella'' infections are arthritis, urinary tract infection, infection of the central nervous system, bone infection, soft tissue infection, etc.<ref name=salspond>{{cite journal | vauthors = Choi YS, Cho WJ, Yun SH, Lee SY, Park SH, Park JC, Jang EH, Shin HY | title = A case of back pain caused by Salmonella spondylitis -A case report- | journal = Korean Journal of Anesthesiology | volume = 59 | issue = Suppl | pages = S233–S237 | date = December 2010 | pmid = 21286449 | pmc = 3030045 | doi = 10.4097/kjae.2010.59.S.S233 }}</ref>  Infection may remain as the latent form for a long time, and when the function of [[Mononuclear phagocyte system|reticular endothelial cells]] is deteriorated, it may become activated and consequently, it may secondarily induce spreading infection in the bone several months or several years after acute salmonellosis.<ref name=salspond/>

A 2018 [[Imperial College London]] study also shows how salmonella disrupt specific arms of the [[immune system]] (e.g. 3 of 5 [[NF-kappaB]] proteins) using a family of [[zinc metalloproteinase]] effectors, leaving others untouched.<ref>{{cite news | url=https://www.sciencedaily.com/releases/2018/09/180928162255.htm | title=Bacterial protein mimics DNA to sabotage cells' defenses: Study reveals details of Salmonella infections| newspaper=Sciencedaily}}</ref> Salmonella thyroid abscess has also been reported.<ref>{{cite journal | vauthors = Sahli M, Hemmaoui B, Errami N, Benariba F | title = Salmonella thyroid abscess | journal = European Annals of Otorhinolaryngology, Head and Neck Diseases | volume = 139 | issue = 1 | pages = 51–52 | date = January 2022 | pmid = 34053890 | doi = 10.1016/j.anorl.2021.05.004 | s2cid = 235256840 | doi-access = free }}</ref>