Editing Protein targeting (section)

=== Both chloroplasts and mitochondria ===
Many proteins are needed in both mitochondria and chloroplasts.<ref>{{cite journal | vauthors = Sharma M, Bennewitz B, Klösgen RB | title = Rather rule than exception? How to evaluate the relevance of dual protein targeting to mitochondria and chloroplasts | journal = Photosynthesis Research | volume = 138 | issue = 3 | pages = 335–343 | date = December 2018 | pmid = 29946965 | doi = 10.1007/s11120-018-0543-7 | bibcode = 2018PhoRe.138..335S | s2cid = 49427254 }}</ref> In general the dual-targeting peptide is of intermediate character to the two specific ones. The targeting peptides of these [[protein]]s have a high content of basic and [[hydrophobic]] [[amino acids]], a low content of negatively charged [[amino acids]]. They have a lower content of alanine and a higher content of leucine and phenylalanine. The dual targeted proteins have a more hydrophobic targeting peptide than both mitochondrial and chloroplastic ones. However, it is tedious to predict if a peptide is dual-targeted or not based on its [[Physiochemical|physio-chemical]] characteristics.