Editing Mutagen (section)

=== Bacterial ===
{{main|Ames test}}
* '''Ames test''' – This is the most commonly used test, and ''[[Salmonella typhimurium]]'' strains deficient in [[histidine]] biosynthesis are used in this test. The test checks for mutants that can revert to wild-type. It is an easy, inexpensive and convenient initial screen for mutagens.
* '''Resistance to 8-azaguanine in ''S. typhimurium''''' – Similar to Ames test, but instead of reverse mutation, it checks for forward mutation that confer resistance to [[8-Azaguanine]] in a histidine revertant strain.
* '''''Escherichia coli'' systems''' – Both forward and reverse mutation detection system have been modified for use in ''[[Escherichia coli|E. coli]]''. [[Tryptophan]]-deficient mutant is used for the reverse mutation, while galactose utility or resistance to 5-methyltryptophan may be used for forward mutation.
* '''DNA repair''' – ''E. coli'' and ''[[Bacillus subtilis]]'' strains deficient in DNA repair may be used to detect mutagens by their effect on the growth of these cells through DNA damage.