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Major depressive disorder
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===Lifestyle=== {{further|Neurobiological effects of physical exercise#Major depressive disorder}} [[File:Soccer football informal in Manipur India cropped.jpg|thumb|Physical exercise is one recommended way to manage mild depression.]]<!-- The text says recommended for major depression, the caption says for mild depression--> [[Physical exercise]] has been found to be effective for major depression, and may be recommended to people who are willing, motivated, and healthy enough to participate in an exercise program as treatment.<ref>{{cite journal |vauthors=Josefsson T, Lindwall M, Archer T |title=Physical exercise intervention in depressive disorders: meta-analysis and systematic review |journal=Scandinavian Journal of Medicine & Science in Sports |volume=24 |issue=2 |pages=259β72 |date=April 2014 |pmid=23362828 |doi=10.1111/sms.12050 |s2cid=29351791 |doi-access=free }}</ref><ref name="m647">{{cite journal |last1=Blumenthal |first1=James A. |last2=Rozanski |first2=Alan |title=Exercise as a therapeutic modality for the prevention and treatment of depression |journal=Progress in Cardiovascular Diseases |volume=77 |date=2023 |pmid=36848966 |pmc=10225323 |doi=10.1016/j.pcad.2023.02.008 |doi-access=free |pages=50β58}}</ref> It is equivalent to the use of medications or psychological therapies in most people.<ref name="Coo2013" /> In older people it does appear to decrease depression.<ref name="y793">{{cite journal |last1=Tang |first1=Lili |last2=Zhang |first2=Lin |last3=Liu |first3=Yanbo |last4=Li |first4=Yan |last5=Yang |first5=Lijuan |last6=Zou |first6=Mingxuan |last7=Yang |first7=Huiran |last8=Zhu |first8=Lingyu |last9=Du |first9=Ruihong |last10=Shen |first10=Ye |last11=Li |first11=Haoyu |last12=Yang |first12=Yong |last13=Li |first13=Zhijun |title=Optimal dose and type of exercise to improve depressive symptoms in older adults: a systematic review and network meta-analysis |journal=BMC Geriatrics |volume=24 |issue=1 |date=7 June 2024 |issn=1471-2318 |pmid=38849780 |pmc=11157862 |doi=10.1186/s12877-024-05118-7 |doi-access=free |page=505}}</ref> Sleep and diet may also play a role in depression, and interventions in these areas may be an effective add-on to conventional methods.<ref name="z728">{{cite journal |last1=Wong |first1=Vincent Wing-Hei |last2=Ho |first2=Fiona Yan-Yee |last3=Shi |first3=Nga-Kwan |last4=Sarris |first4=Jerome |last5=Chung |first5=Ka-Fai |last6=Yeung |first6=Wing-Fai |title=Lifestyle medicine for depression: A meta-analysis of randomized controlled trials |journal=Journal of Affective Disorders |volume=284 |date=2021 |doi=10.1016/j.jad.2021.02.012 |doi-access=free |pages=203β216 |pmid=33609955 |hdl=10397/103774 |url=http://ira.lib.polyu.edu.hk/bitstream/10397/103774/1/Yeung_Lifestyle_Medicine_Depression.pdf |access-date=28 February 2025}}</ref> In studies, [[smoking cessation]] has benefits in depression.<ref name="d893">{{cite journal |last1=Taylor |first1=Gemma MJ |last2=Lindson |first2=Nicola |last3=Farley |first3=Amanda |last4=Leinberger-Jabari |first4=Andrea |last5=Sawyer |first5=Katherine |last6=te Water NaudΓ© |first6=Rebecca |last7=Theodoulou |first7=Annika |last8=King |first8=Naomi |last9=Burke |first9=Chloe |last10=Aveyard |first10=Paul |title=Smoking cessation for improving mental health |journal=Cochrane Database of Systematic Reviews |volume=2021 |issue=3 |date=9 March 2021 |pages=CD013522 |pmid=33687070 |pmc=8121093 |doi=10.1002/14651858.CD013522.pub2 |doi-access=free |url=http://pure-oai.bham.ac.uk/ws/files/116308750/TaylorG2021Smoking.pdf |access-date=28 February 2025 }}</ref>
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