Editing Little Orphan Annie (section)

==Parodies, imitations and cultural citations==
The characters and concept of ''Little Orphan Annie'' have been influential in comics and other media during the original run and continuing into the modern day. Between 1936 and October 17, 1959, the comic strip [[Belinda (comic strip)|''Belinda Blue-Eyes'']] (later shortened to ''Belinda'') ran in the United Kingdom in the ''[[Daily Mirror]]''. Writers Bill Connor and Don Freeman and artists Stephen Dowling and Tony Royle all worked on the strip over the years. In ''The Penguin Book of Comics'' Belinda is described as "a perpetual waif, a British counterpart to the transatlantic ''Little Orphan Annie''."<ref>{{Cite book |author=Perry, George |title=The Penguin Book of Comics |author2=Aldridge, Alan |publisher=Penguin |year=1967}}</ref><ref>{{cite web |title=Tony Royle |url=http://lambiek.net/artists/r/royle_tony.htm |website=lambiek.net}}</ref> The strip also influenced ''[[Little Annie Rooney]]'' (Jan. 10, 1927–1966) and ''[[Frankie Doodle]]'' (1934-1938).{{Citation needed|date=September 2022}}

In 1995, ''Little Orphan Annie'' was one of 20 American comic strips included in the [[Comic Strip Classics]] series of commemorative U.S. postage stamps.{{Citation needed|date=September 2022}} Rapper [[Jay-Z]] has referenced ''Little Orphan Annie'' in at least two of his songs,<ref>{{cite web |title=JAY-Z: Brooklyn (Go Hard) lyrics |url=http://www.lyricsreg.com/lyrics/jay-z/Brooklyn+Go+Hard/ |website=www.lyricsreg.com}}</ref><ref>{{cite web |title=Jay-Z Dirt Off Your Shoulder Lyrics |url=http://www.lyrics007.com/Jay-Z+Lyrics/Dirt+Off+Your+Shoulder+Lyrics.html |website=www.lyrics007.com|date=October 28, 2023 }}</ref> as well as sampling "It's the Hard Knock Life" for "[[Hard Knock Life (Ghetto Anthem)]]" (1998).<ref>{{cite magazine |author=Taylor, Chuck |author-link=Chuck Taylor (music journalist) |date=October 24, 1998 |title=Reviews & Previews: Singles |url=https://worldradiohistory.com/Archive-Billboard/90s/1998/BB-1998-10-24.pdf |magazine=[[Billboard (magazine)|Billboard]] |page=22 |access-date=December 6, 2020}}</ref> On the album cover of punk rock cover band [[Me First and the Gimme Gimmes]]' 1999 album ''[[Are a Drag]]'', rhythm guitarist and [[Lagwagon]] vocalist [[Joey Cape]] is dressed as Annie, as she was depicted in the [[Annie (1982 film)|1982 film]].{{Citation needed|date=September 2022}} Starting in 2014, red-haired comedian [[Michelle Wolf]] appeared on numerous segments on ''[[Late Night with Conan O'Brien|Late Night]]'' as her fictional persona, "Grown-Up Annie", an adult version of Little Orphan Annie.<ref>{{cite web |last=Petski |first=Denise |date=4 April 2016 |title='Daily Show With Trevor Noah' Adds Michelle Wolf As On-Air Contributor & Writer |url=https://deadline.com/2016/04/the-daily-show-with-trevor-noah-michelle-wolf-contributor-writer-1201731581/ |access-date=8 February 2017 |website=[[Deadline Hollywood]]}}</ref><ref>{{cite web |author=Blumenfeld, Zach |date=April 4, 2016 |title=Comedian Michelle Wolf Joins The Daily Show As Writer, Contributor |url=https://www.pastemagazine.com/articles/2016/04/comedian-michelle-wolf-joins-the-daily-show-as-wri.html |access-date=April 9, 2016 |work=Paste}}</ref>

In medicine, "Orphan Annie eye" (empty or "ground glass") [[nucleus (cell)|nuclei]] are a characteristic [[histology|histological]] finding in [[Papillary thyroid cancer|papillary carcinoma]] of the [[thyroid gland]].<ref>{{Cite journal |last=Bavle |first=Radhika M |title=Orphan annie-eye nuclei |date=2013 |journal=Journal of Oral and Maxillofacial Pathology|volume=17 |issue=2 |pages=154–155 |doi=10.4103/0973-029X.119737 |issn=0973-029X |pmc=3830218 |pmid=24250070 |doi-access=free }}</ref>

Many comics, cartoons, TV shows and other media have parodied or referenced the name ''Little Orphan Annie''. Early examples "Little Arf 'n Nonnie" and "Lulu Arfin' Nanny" appear in the [[Walt Kelly]] strip ''[[Pogo (comics)|Pogo]]''.{{Citation needed|date=September 2022}} "Little Orphan Melvin" appears in the ninth issue of ''[[Mad (magazine)|Mad]]'' magazine by [[Harvey Kurtzman]] and [[Wally Wood]], published 1952.{{Citation needed|date=September 2022}} Kurtzman later produced a long-running erotic comic for ''[[Playboy]]'' called ''[[Little Annie Fanny]].'' In ''[[The Fabulous Furry Freak Brothers]]'', [[Gilbert Shelton]] satirized the strip as "Little Orphan Amphetamine".{{Citation needed|date=September 2022}} 1980s children's program ''[[You Can't Do That on Television]]'' parodied the character as "Little Orphan Andrea" in its "Adoption" episode, later banned.{{Citation needed|date=September 2022}} The [[Teenage Mutant Ninja Turtles (Mirage Studios)|''Teenage Mutant Ninja Turtles'']] comics by [[Mirage Studios]] feature a fictional toy line named "Little Orphan Aliens".<ref>''Teenage Mutant Ninja Turtles'' (Mirage Studios): "The Christmas Aliens" (Kevin Eastman and Peter Laird; ''Micro-Series #3: Michelangelo'', December 1985), and "Alien Invaders" (Jim Lawson; ''Tales of the TMNT'' Vol.2 #53, December 2008)</ref>