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=== RNA interference === [[RNA interference]] (RNAi) uses segments of RNA to fatally [[Gene silencing|silence]] crucial [[Gene silencing pesticide|insect genes]].<ref name="Zhu-Palli-2020">{{cite journal | last1=Zhu | first1=Kun Yan | last2=Palli | first2=Subba Reddy | title=Mechanisms, Applications, and Challenges of Insect RNA Interference | journal=[[Annual Review of Entomology]] | publisher=[[Annual Reviews (publisher)|Annual Reviews]] | volume=65 | issue=1 | date=2020-01-07 | issn=0066-4170 | doi=10.1146/annurev-ento-011019-025224 | pages=293β311| pmid=31610134 | s2cid=204702574 | pmc=9939233 }}</ref> In 2024 two uses of RNAi have been registered by the authorities for use: G[[Genetically modified crops|enetic modification]] of a crop to introduce a gene coding for an RNAi fragment, and spraying double stranded RNA fragments onto a field.<ref name=":8" /> [[Monsanto]] introduced the trait DvSnf7 which expresses a double-stranded RNA transcript containing a 240 bp fragment of the WCR Snf7 gene of the [[Western corn rootworm|Western Corn Rootworm]].<ref name=":7" /> GreenLight Biosciences introduced Ledprona, a formulation of double stranded RNA as a spray for potato fields. It targets the essential gene for [[Proteasome subunit beta type-5|proteasome subunit beta type-]]5 (PSMB5) in the [[Colorado potato beetle]].<ref name=":8" />
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