Editing Tocopherol (section)

===Supplement popularity over time===
In the US, the popularity for vitamin E as a dietary supplement may have peaked around 2000. The [[Nurses' Health Study]] (NHS) and the Health Professionals Follow-up Study (HPFS) tracked dietary supplement use by people over the age of 40 during years 1986–2006. For women, user prevalence was 16.1% in 1986, 46.2% in 1998, 44.3% in 2002, but had decreased to 19.8% in 2006. Similarly, for men, prevalence for same years was 18.9%, 52.0%, 49.4%, and 24.5%. The authors theorized that declining use in these health science aware populations may have been due to publications of studies that showed either no benefits or negative consequences from vitamin E supplements.<ref>{{cite journal | vauthors = Kim HJ, Giovannucci E, Rosner B, Willett WC, Cho E | title = Longitudinal and secular trends in dietary supplement use: Nurses' Health Study and Health Professionals Follow-Up Study, 1986-2006 | journal = Journal of the Academy of Nutrition and Dietetics | volume = 114 | issue = 3 | pages = 436–43 | date = March 2014 | pmid = 24119503 | pmc = 3944223 | doi = 10.1016/j.jand.2013.07.039 }}</ref> There is other evidence for declining use of vitamin E. Within the U.S. military services, vitamin prescriptions written for active, reserve and retired military, and their dependents, were tracked over years 2007–2011. Vitamin E prescriptions decreased by 53% while vitamin C remained constant and vitamin D increased by 454%.<ref>{{cite journal | vauthors = Morioka TY, Bolin JT, Attipoe S, Jones DR, Stephens MB, Deuster PA | title = Trends in Vitamin A, C, D, E, K Supplement Prescriptions From Military Treatment Facilities: 2007 to 2011 | journal = Military Medicine | volume = 180 | issue = 7 | pages = 748–53 | date = July 2015 | pmid = 26126244 | doi = 10.7205/MILMED-D-14-00511 | doi-access = free }}</ref> A report on vitamin E sales volume in the USA documented a 50% decrease between 2000 and 2006,<ref>{{cite journal | vauthors = Tilburt JC, Emanuel EJ, Miller FG | title = Does the evidence make a difference in consumer behavior? Sales of supplements before and after publication of negative research results | journal = Journal of General Internal Medicine | volume = 23 | issue = 9 | pages = 1495–8 | date = September 2008 | pmid = 18618194 | pmc = 2518024 | doi = 10.1007/s11606-008-0704-z }}</ref> with a significant cause attributed to a well-publicized meta-analysis that had concluded that high-dosage vitamin E increased all-cause mortality.<ref name=Miller2005>{{cite journal | vauthors = Miller ER, Pastor-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E | title = Meta-analysis: high-dosage vitamin E supplementation may increase all-cause mortality | journal = Annals of Internal Medicine | volume = 142 | issue = 1 | pages = 37–46 | date = January 2005 | pmid = 15537682 | doi = 10.7326/0003-4819-142-1-200501040-00110 | s2cid = 35030072 }}</ref>