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===Osteoporosis and fractures=== Studies have found that the use of statins may protect against getting osteoporosis and fractures or may induce osteoporosis and fractures.<ref>{{cite journal | vauthors = Lin TK, Chou P, Lin CH, Hung YJ, Jong GP | title = Long-term effect of statins on the risk of new-onset osteoporosis: A nationwide population-based cohort study | journal = PLOS ONE | volume = 13 | issue = 5 | pages = e0196713 | date = 2018 | pmid = 29723231 | pmc = 5933736 | doi = 10.1371/journal.pone.0196713 | doi-access = free | title-link = doi | bibcode = 2018PLoSO..1396713L }}</ref><ref>{{cite journal | vauthors = Wang Z, Li Y, Zhou F, Piao Z, Hao J | title = Effects of Statins on Bone Mineral Density and Fracture Risk: A PRISMA-compliant Systematic Review and Meta-Analysis | journal = Medicine | volume = 95 | issue = 22 | pages = e3042 | date = May 2016 | pmid = 27258488 | pmc = 4900696 | doi = 10.1097/MD.0000000000003042 }}</ref><ref>{{cite journal | vauthors = An T, Hao J, Sun S, Li R, Yang M, Cheng G, Zou M | title = Efficacy of statins for osteoporosis: a systematic review and meta-analysis | journal = Osteoporosis International | volume = 28 | issue = 1 | pages = 47–57 | date = January 2017 | pmid = 27888285 | doi = 10.1007/s00198-016-3844-8 | s2cid = 4723680 }}</ref><ref>{{cite journal | vauthors = Larsson BA, Sundh D, Mellström D, Axelsson KF, Nilsson AG, Lorentzon M | title = Association Between Cortical Bone Microstructure and Statin Use in Older Women | journal = The Journal of Clinical Endocrinology and Metabolism | volume = 104 | issue = 2 | pages = 250–257 | date = February 2019 | pmid = 30423123 | doi = 10.1210/jc.2018-02054 | doi-access = free | title-link = doi }}</ref> A cross-sectional retrospective analysis of the entire Austrian population found that the risk of getting osteoporosis is dependent on the dose used.<ref>{{cite journal | vauthors = Leutner M, Matzhold C, Bellach L, Deischinger C, Harreiter J, Thurner S, Klimek P, Kautzky-Willer A | title = Diagnosis of osteoporosis in statin-treated patients is dose-dependent | journal = Annals of the Rheumatic Diseases | volume = 78 | issue = 12 | pages = 1706–1711 | date = December 2019 | pmid = 31558481 | pmc = 6900255 | doi = 10.1136/annrheumdis-2019-215714 }}</ref>
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