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====Microbiota==== {{Main|Lung microbiota}} There is a large presence of [[microorganism]]s in the lungs known as the [[lung microbiota]] that interacts with the airway epithelial cells; an interaction of probable importance in maintaining homeostasis. The [[Microbiota#Humans|microbiota]] is complex and dynamic in healthy people, and altered in diseases such as [[asthma]] and [[COPD]]. For example significant changes can take place in COPD following infection with [[rhinovirus]].<ref name="Hiemstra">{{cite journal |last1=Hiemstra |first1=PS |last2=McCray PB |first2=Jr |last3=Bals |first3=R |title=The innate immune function of airway epithelial cells in inflammatory lung disease. |journal=The European Respiratory Journal |date=April 2015 |volume=45 |issue=4 |pages=1150β62 |doi=10.1183/09031936.00141514 |pmid=25700381|pmc=4719567 }}</ref> [[Fungus|Fungal]] [[genera]] that are commonly found as [[mycobiota]] in the microbiota include ''[[Candida (fungus)|Candida]]'', ''[[Malassezia]]'', ''[[Saccharomyces]]'', and ''[[Aspergillus]]''.<ref name="Cui">{{cite journal |vauthors=Cui L, Morris A, Ghedin E |title=The human mycobiome in health and disease |journal=Genome Med |volume=5 |issue=7 |pages=63 |date=2013 |pmid=23899327 |pmc=3978422 |doi=10.1186/gm467 |url= |doi-access=free }}</ref><ref name="Richardson">{{cite journal |last1=Richardson |first1=M |last2=Bowyer |first2=P |last3=Sabino |first3=R |title=The human lung and Aspergillus: You are what you breathe in? |journal=Medical Mycology |date=1 April 2019 |volume=57 |issue=Supplement_2 |pages=S145βS154 |doi=10.1093/mmy/myy149 |pmid=30816978|pmc=6394755 }}</ref>
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