Editing Ehlers–Danlos syndrome (section)

===Vascular===
Vascular EDS (vEDS; formerly categorized as type 4) is identified by skin that is thin, translucent, extremely fragile, and bruises easily. It is also characterized by fragile blood vessels and organs that can easily rupture. Affected people are frequently short, and have thin scalp hair. It also has characteristic facial features, including large eyes, an undersized chin, sunken cheeks, a thin nose and lips, and ears without lobes.<ref name="Eagleton2016">{{cite journal | vauthors = Eagleton MJ | title = Arterial complications of vascular Ehlers–Danlos syndrome | journal = Journal of Vascular Surgery | volume = 64 | issue = 6 | pages = 1869–1880 | date = December 2016 | pmid = 27687326 | doi = 10.1016/j.jvs.2016.06.120 | url = https://www.jvascsurg.org/article/S0741-5214(16)30876-X/fulltext | doi-access = free}} {{open access}}</ref> Joint hypermobility is present, but generally confined to the small joints (fingers, toes). Other common features include [[Clubfoot|club foot]], tendon and/or muscle rupture, [[acrogeria]] (premature aging of the skin of the hands and feet), early-onset [[varicose veins]], [[pneumothorax]] (collapse of a lung), the recession of the gums, and a decreased amount of fat under the skin.<ref name="GARD2017" /> It can be caused by the variations in the ''[[COL3A1]]'' gene.<ref name="Eagleton2016" /> Rarely, ''[[COL1A1]]'' variations can also cause it.<ref name="Malfait_2017"/>