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===Cross-breeds=== {{main|Dog crossbreed}} {{See also|List of dog crossbreeds}} A [[dog crossbreed]] is the result of mating two different breeds.<ref>{{cite web|title=cross-breed|work=Oxford Dictionaries|publisher=Oxford University Press|year=2014|url=http://www.oxforddictionaries.com/definition/english/cross-breed|archive-url=https://web.archive.org/web/20120717215401/http://oxforddictionaries.com/definition/english/cross-breed|url-status=dead|archive-date=17 July 2012}}</ref> "Designer Dog" became a fad in the late 20th century.<ref>{{Cite web|url=https://vcahospitals.com/know-your-pet/designer-dog-breeds|title=VCA Hospitals|last=Buzhardt|first=Lynn|date=2016|website=VCA}}</ref><ref>{{Cite web|url=https://www.showqualitydogs.com/indian-dog-breeds/best-dog-breeds-in-indian-climate/|title=Show Quality Dogs |date=2020|website=show quality dogs}}</ref> Dog crossbreeds are combinations of lineages of the [[domestic dog]]; they are distinguished from [[Canid hybrid|canid hybrids]], which are interspecific crosses between ''Canis'' species (wolves, coyotes, jackals, etc.). Notable canid hybrids include the [[coydog]], [[coywolf]], [[dingo–dog hybrid]], [[jackal–dog hybrid]], and [[wolfdog]].<ref>{{cite web |last=Bennett |first=Laura |date=December 10, 2007 |title=Pet Industry Trends for 2008 |url=http://www.smallbiztrends.com/2007/12/pet-industry-trends-for-2008.html |archive-url=https://web.archive.org/web/20080704210718/http://www.smallbiztrends.com/2007/12/pet-industry-trends-for-2008.html |archive-date=4 July 2008 |website=smallbiztrends.com |quote=2008 will see the rapid growth of the puppy farm [[crossbreed]]s to take advantage of the inflated prices people are paying for these dogs.}}</ref><ref>{{cite news |last=Patterson |first=Melissa |date=July 23, 2008 |title=Not all cute and cuddly in land of 'designer dogs,' |work=[[Chicago Tribune]] |url=http://www.chicagotribune.com/news/local/chicago/chi-hybrid-dogs-23-jul23,0,1726044.story |archive-url=https://web.archive.org/web/20081006151823/http://www.chicagotribune.com/news/local/chicago/chi-hybrid-dogs-23-jul23,0,1726044.story |archive-date=6 October 2008 |quote=[crossbreed designer dog puppies] often go for more money than purebreds, which can range from $200 to $2,000 per dog.}}</ref><ref>{{cite news |last=Caesar |first=Ed |date=8 March 2007 |title=Hounded out: Fur and loathing in the dog world |newspaper=The Independent |url=https://www.independent.co.uk/news/uk/this-britain/hounded-out-fur-and-loathing-in-the-dog-world-439360.html |quote=the stampede to acquire one (designer dog) has become so furious that puppies now sell for as much as £2,000.}}</ref><ref>{{cite web |title=Designer Dogs are the Rage |url=http://www.designerdoggies.com/Hybridsinthenews.html |archive-url=https://web.archive.org/web/20080704210718/http://www.designerdoggies.com/Hybridsinthenews.html |archive-date=4 July 2008 |website=designerdoggies.com |quote=the Beagle is one of the lowest priced purebred dogs, yet the Puggle often sells for much more than the purebred Pug.}}</ref> Historically, crosses between dogs of different types were more well accepted at a time when modern purebred breeds (based on the [[eugenics]] principles) did not yet exist.<ref>{{Cite book |last=Brandow |first=Michael |url=https://dogcutieshq.com/ |title=Dogcutieshq |date=2015 |publisher=Beacon Press |isbn=9780807033432 |language=en}}</ref><ref name=":0">{{Cite book |last=Walsh |first=John Henry |url=https://archive.org/details/doginhealthandd00walsgoog |title=The dog, in health and disease, by Stonehenge |date=1859 |language=en}}</ref> Some crossbred dogs, created by breeding two purebred dogs of different breeds, may have the advantage of [[heterosis]], or crossbreed vigor. This advantage can be progressively diluted when two crossbreeds are bred in the attempt to create a breed, narrowing the gene pool. The best way to continue taking advantage of crossbreed vigor is from the breeding of dogs of purebred ancestry, as this vigor is typically seen only in the first generation cross of two purebred animals of separate breeds, thus taking advantage of [[genetic diversity]]. <ref name="Csányi">{{cite book |last=Csányi |first=Vilmos |title=If Dogs Could Talk |date=2005 |publisher=North Point Press |isbn=978-0-86547-686-8 |edition=First American |location=New York |pages=285–286 |translator=Richard E. Quandt}}</ref><ref>{{cite journal |last1=Birchler |first1=James A. |last2=Yao |first2=Hong |last3=Chudalayandi |first3=Sivanandan |date=29 August 2006 |title=Unraveling the genetic basis of hybrid vigor |journal=Proceedings of the National Academy of Sciences of the United States of America |volume=103 |issue=35 |pages=12957–12958 |bibcode=2006PNAS..10312957B |doi=10.1073/pnas.0605627103 |pmc=1559732 |pmid=16938847 |doi-access=free}}</ref>
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