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Brugada syndrome
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== Epidemiology == Between 1 and 30 per 10,000 people are affected by Brugada syndrome.<ref name=GHR2015/><ref name="Pol2017"/> Although those affected are born with the condition, symptoms typically only begin in adulthood. While the rare cases seen in childhood are equally likely to be male or female, in adulthood symptoms occur more frequently in males than females, potentially due to the higher testosterone levels found in men.<ref name="Pol2017" /><ref>{{cite journal | vauthors = Behere SP, Weindling SN | title = Brugada syndrome in children β Stepping into unchartered territory | journal = Annals of Pediatric Cardiology | volume = 10 | issue = 3 | pages = 248β258 | date = September 2017 | pmid = 28928611 | pmc = 5594936 | doi = 10.4103/apc.APC_49_17 | doi-access = free }}</ref> Brugada syndrome is more common in people of [[Asian people|Asian]] descent and is the most common cause of sudden death in young males without known underlying cardiac disease in [[Thailand]] and [[Laos]].<ref name="Pol2017" /><ref name=":1">{{cite journal | vauthors = Brugada J, Brugada P, Brugada R | title = The syndrome of right bundle branch block ST segment elevation in V1 to V3 and sudden death--the Brugada syndrome | journal = Europace | volume = 1 | issue = 3 | pages = 156β66 | date = July 1999 | pmid = 11225790 | doi = 10.1053/eupc.1999.0033 | doi-access = free }}</ref> In these countries Brugada syndrome is likely to be responsible for many cases of sudden unexpected nocturnal death syndrome (SUNDS). Local names vary β in the [[Philippines]] the condition has been known as ''Bangungut'' meaning "a scream followed by sudden death during sleep",<ref name=":1" /> while in Thailand it was known as <em>Lai Tai</em>, and in [[Japan]] <em>Pokkuri</em>.<ref>{{cite journal | vauthors = Nakajima K, Takeichi S, Nakajima Y, Fujita MQ | title = Pokkuri Death Syndrome; sudden cardiac death cases without coronary atherosclerosis in South Asian young males | journal = Forensic Science International | volume = 207 | issue = 1β3 | pages = 6β13 | date = April 2011 | pmid = 21084168 | doi = 10.1016/j.forsciint.2010.10.018 }}</ref><ref name=":0" /> Type 1 Brugada ECG patterns are seen more frequently in Asian populations (0β0.36%) than those in Europe (0β0.25%) and the United States (0.03%). Similarly, Type 2 and Type 3 ECG patterns are more prevalent in Asia (0.12β2.23%) than in Europe (0.0β0.6%) or the United States (0.02%).<ref>{{cite journal | vauthors = Mizusawa Y, Wilde AA | title = Brugada syndrome | journal = Circulation: Arrhythmia and Electrophysiology | volume = 5 | issue = 3 | pages = 606β16 | date = June 2012 | pmid = 22715240 | doi = 10.1161/CIRCEP.111.964577 | doi-access = free }}</ref>
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